Advances in MR imaging for cervical spondylotic myelopathy
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- 作者：Benjamin M. Ellingson (1)
Noriko Salamon (1)
Langston T. Holly (2)
1. Department of Radiology ; David Geffen UCLA School of Medicine ; Los Angeles ; USA
2. Department of Neurosurgery and Orthopaedics ; David Geffen UCLA School of Medicine ; 10833 Leconte Avenue ; Los Angeles ; CA ; 90095 ; USA - 关键词：Cervical ; Spinal cord ; DTI ; MRI ; Myelopathy
- 刊名：European Spine Journal
- 出版年：2015
- 出版时间：April 2015
- 年：2015
- 卷：24
- 期：2-supp
- 页码：197-208
- 全文大小：1,623 KB
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- 刊物主题：Medicine & Public Health
Surgical Orthopedics
Neurosurgery - 出版者：Springer Berlin / Heidelberg
- ISSN：1432-0932
文摘
Purpose To outline the pathogenesis of cervical spondylotic myelopathy (CSM), the correlative abnormalities observed on standard magnetic resonance imaging (MRI), the biological implications and current status of diffusion tensor imaging (DTI), and MR spectroscopy (MRS) as clinical tools, and future directions of MR technology in the management of CSM patients. Methods A systematic review of the pathogenesis and current state-of-the-art in MR imaging technology for CSM was performed. Results CSM is caused by progressive, degenerative, vertebral column abnormalities that result in spinal cord damage related to both primary mechanical and secondary biological injuries. The T2 signal change on conventional MRI is most commonly associated with neurological deficits, but tends not to be a sensitive predictor of recovery of function. DTI and MRS show altered microstructure and biochemistry that reflect patient-specific pathogenesis. Conclusion Advanced imaging techniques, including DTI and MRS, show higher sensitivity to microstructural and biochemical changes within the cord, and may aid in management of CSM patients.