Demodex treatment in external ocular disease: the outcomes of a Tasmanian case series

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• 作者：Stephen G. Nicholls ; Carmen L. Oakley ; Andrea Tan…
• 关键词：Demodex spp ; External ocular disease ; Dry eye disease ; Tea tree oil ; Blepharitis
• 刊名：International Ophthalmology
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：36
• 期：5
• 页码：691-696
• 全文大小：339 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Ophthalmology
  
• 出版者：Springer Netherlands
• ISSN：1573-2630
• 卷排序：36

文摘

Demodex species (spp.) have previously been implicated in the pathogenesis of blepharitis. This study aims to correlate improvement in symptoms of external ocular disease with treatment of underlying Demodex spp. This is a prospective, observational case series of patients with chronic external ocular disease. Demodicosis was confirmed by microscopic examination of epilated eyelashes. The main outcome measure was response to the treatment (5 % tee tree oil) in regard to change in subjective symptoms utilising a symptom-based patient questionnaire assessment. Overall patients had a good response to the treatment in terms of improvement or resolution of symptoms, with 91 % of patients reporting at least some improvement in symptoms. The treatment of underlying Demodex spp. appears to result in improvement of symptoms in patients with long standing external ocular disease and underlying Demodex spp. infestation.