Relationship between the temperature and the acoustic nonlinearity parameter in biological tissues

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• 作者：Ying Lu (1)
  Xiaozhou Liu (1)
  Xiufen Gong (1)
  Dong Zhang (1)
  
• 关键词：acoustic nonlinearity parameter ; noninvasive temperature estimation ; ultrasound therapy ; HIFU ; thermocouple
• 刊名：Chinese Science Bulletin
• 出版年：2004
• 出版时间：November 2004
• 年：2004
• 卷：49
• 期：22
• 页码：2360-2363
• 全文大小：278KB
• 参考文献：1. Roberto, M.-M., Christakis, A. D., Noninvasive temperature estimation in tissue via ultrasound echo-shift, Part I. Analytical model, J. Acoust. Soc. Am., 1996, 100(4): 2514鈥?521. CrossRef
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  6. Gong, X.F., Zhu, Z.M, Shi, T. et al., Determination of acoustic parameter for biological tissues using FAIS and ITD methods, J. Acoust. Soc. Am., 1989, 86(1): 1鈥?. CrossRef
  7. Lu, R.R., Zhang, D., Gong, X.F. et al., The measurement of reflected second harmonics and nonlinearity parameter of media using a transducer with complex structure, Acta Acustica (in Chinese), 2001, 26(6): 512鈥?15.
  8. Cao Yuzhang, Heat Ttransfer, Beijing: Beijing University of Aeronautics and Astronautics Press, 2001.
  9. Gong, X. F., Zhang, D., Liu, J. H. et al., Study of acoustic nonlinearity parameter imaging methods in reflection mode for biological tissues, J. Acoustic. Soc. Am., 2004, 116(3): 1819鈥?825.[DOI] CrossRef
  
• 作者单位：Ying Lu (1)
  Xiaozhou Liu (1)
  Xiufen Gong (1)
  Dong Zhang (1)
  
  1. State Key Laboratory of Modern Acoustics, Institute of Acoustics, Nanjing University, 210093, Nanjing, China
  
• ISSN：1861-9541

文摘

Recently with the rapid development of the high-intensity focused ultrasound (HIFU) in biomedical ultrasound, much attention has been paid to the noninvasive temperature estimation in biological tissue in order to determine the region and degree of the ultrasound-induced lesions. In ultrasound hyperthermal therapy it is highly desirable to study the real-time noninvasive monitoring of temperature distribution in biological tissue. In this paper, the relationship between the nonlinearity parameterB/A and the temperature in biological tissue is studied and compared with the theoretical model as well as the experimental results from the thermocouple. Results indicated thatB/A could be used as an effective tool to monitor the temperature distribution in biological media.