Ochratoxin A in brewer’s yeast used as food supplement

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• 作者：Christoph Gottschalk ; Barbara Biermaier ; Madeleine Gross…
• 关键词：Mycotoxin ; Ochratoxin A ; Dietary supplement ; Saccharomyces cerevisiae
• 刊名：Mycotoxin Research
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：32
• 期：1
• 页码：1-5
• 全文大小：349 KB
• 参考文献：Bevilacqua A, Petruzzi L, Corbo MR, Baiano A, Garofalo C, Sinigaglia M (2014) Ochratoxin A released back into the medium by Saccharomyces cerevisiae as a function of the strain, washing medium and fermentative conditions. J Sci Food Agric 94(15):3291–3295. doi:10.​1002/​jsfa.​6683 CrossRef PubMed
  Cholmakov-Bodechtel C, Wolff J, Gareis M, Bresch H, Engel G, Majerus P, Rosner H, Schneider R (2000) Ochratoxin A: representative food consumption survey and epidemiological analysis. Archiv Fur Lebensmittelhygiene 51(4-5):111–115
  EFSA (2006) Opinion of the scientific panel on contaminants in the food chain [CONTAM] related to ochratoxin A in food. EFSA CONTAM Panel (EFSA Panel on Contaminants in the Food Chain) 365:1–56. doi:10.​2903/​j.​efsa.​2006.​365
  Gareis M (2002) Ochratoxin A in Brewer's yeast used as nutrient supplement. Mycotoxin Res 18(Suppl 2):128–131. doi:10.​1007/​bf02946080 CrossRef PubMed
  Goncalves BL, Rosim RE, Fernandes de Oliveira CA, Corassin CH (2015) The in vitro ability of different Saccharomyces cerevisiae-based products to bind aflatoxin B-1. Food Control 47:298–300. doi:10.​1016/​j.​foodcont.​2014.​07.​024 CrossRef
  Kapetanakou AE, Kollias JN, Drosinos EH, Skandamis PN (2012) Inhibition of A. carbonarius growth and reduction of ochratoxin A by bacteria and yeast composites of technological importance in culture media and beverages. Int J Food Microbiol 152(3):91–99. doi:10.​1016/​j.​ijfoodmicro.​2011.​09.​010 CrossRef PubMed
  Miraglia M, Brera C (2002) Assessment of dietary intake of ochratoxin A by the population of EU member states. Reports on tasks for scientific cooperation Reports of experts participating in SCOOP Task 3(7)
  Moslehi-Jenabian S, Lindegaard L, Jespersen L (2010) Beneficial effects of probiotic and food borne yeasts on human health. Nutrients 2(4):449–473PubMedCentral CrossRef PubMed
  Petruzzi L, Corbo MR, Baiano A, Beneduce L, Sinigaglia M, Bevilacqua A (2015) In vivo stability of the complex ochratoxin A—Saccharomyces cerevisiae starter strains. Food Control 50:516–520. doi:10.​1016/​j.​foodcont.​2014.​09.​042 CrossRef
  Petruzzi L, Corbo MR, Sinigaglia M, Bevilacqua A (2014) Yeast cells as adsorbing tools to remove ochratoxin A in a model wine. Int J Food Sci Technol 49(3):936–940CrossRef
  Piotrowska M, Masek A (2015) Saccharomyces cerevisiae cell wall components as tools for ochratoxin A decontamination. Toxins 7(4):1151–1162. doi:10.​3390/​toxins7041151 PubMedCentral CrossRef PubMed
  Pizzolitto RP, Salvano MA, Dalcero AM (2012) Analysis of fumonisin B-1 removal by microorganisms in co-occurrence with aflatoxin B-1 and the nature of the binding process. Int J Food Microbiol 156(3):214–221. doi:10.​1016/​j.​ijfoodmicro.​2012.​03.​024 CrossRef PubMed
  Poloni V, Dogi C, Pereyra CM, Juri MGF, Kohler P, Rosa CAR, Dalcero AM, Cavaglieri LR (2015) Potentiation of the effect of a commercial animal feed additive mixed with different probiotic yeast strains on the adsorption of aflatoxin B-1. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 32(6):970–976. doi:10.​1080/​19440049.​2015.​1024761 CrossRef PubMed
  Solfrizzo M, Piemontese L, Gambacorta L, Zivoli R, Longobardi F (2015) Food coloring agents and plant food supplements derived from Vitis vinifera: a new source of human exposure to ochratoxin A. J Agric Food Chem 63(13):3609–3614. doi:10.​1021/​acs.​jafc.​5b00326 CrossRef PubMed
  Trucksess MW, Whitaker TB, Weaver CM, Slate A, Giesbrecht FG, Rader JI, Betz JM (2009) Sampling and analytical variability associated with the determination of total aflatoxins and ochratoxin A in powdered ginger sold as a dietary supplement in capsules. J Agric Food Chem 57(2):321–325. doi:10.​1021/​jf8017854 CrossRef PubMed
  
• 作者单位：Christoph Gottschalk (1)
  Barbara Biermaier (1)
  Madeleine Gross (2)
  Karin Schwaiger (1)
  Manfred Gareis (1)
  
  1. Faculty of Veterinary Medicine, Ludwig-Maximilians-University Munich (LMU), Schoenleutnerstr. 8, 85764, Oberschleissheim, Germany
  2. Institute of Veterinary Food Science, Veterinary Faculty, Justus Liebig University Giessen, Ludwigstr. 21, 35390, Giessen, Germany
  
• 刊物主题：Microbiology; Medical Microbiology; Chemistry/Food Science, general; Medicine/Public Health, general;
• 出版者：Springer Berlin Heidelberg
• ISSN：1867-1632

文摘

Brewer’s yeasts are rich in vitamins of the B-group and contain other nutritive factors; therefore, they are recommended as valuable food supplements for people with special dietary requirements like pregnant women, children, and adolescents, or for people with high physical activity. Additionally, certain strains of brewer’s yeast are known to be capable of adsorbing xenobiotics such as mycotoxins. Because of that, these yeasts are regarded as having positive effects in food, beverage, and feed technology. Their potential to bind mycotoxins such as ochratoxin A (OTA), however, can subsequently lead to a contamination of such brewer’s yeasts used as food supplements. In the present study, we analyzed 46 samples of brewer’s yeasts for the occurrence of OTA by HPLC with fluorescence detector (HPLC-FLD) and for confirmatory measurements by liquid chromatography-tandem mass spectrometry (LC-MS/MS). Nearly 90 % of the samples were contaminated with OTA, the levels ranging from the limit of detection (LOD, 0.01 μg/kg) to 4.2 μg/kg. The mean and median levels of contamination were 0.49 and 0.27 μg/kg, respectively. Based on these results, the additional weekly OTA exposure by regularly consuming such supplements was assessed. Depending on different subpopulations (adults, children) and levels of contamination used for calculation, the additional OTA intake via brewer’s yeast products ranged from 9.3 % (mean case) to 114 % (worst case) of the published mean weekly OTA intake in Germany (adults 279.3 ng, children 195.3 ng). At present, maximum levels for OTA in nutritional supplements like brewer’s yeast do not exist. Based on our results, however, it is recommended that producers of these dietary supplements should include mycotoxin analyses in ongoing and future self-monitoring programs and in product quality checks. Keywords Mycotoxin Ochratoxin A Dietary supplement Saccharomyces cerevisiae