Omission of axillary lymph node dissection for clinically node negative early-stage breast cancer patients

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• 作者：Reiko Kobayashi ; Kenshiro Shiraishi ; Satoru Iwase ; Kuni Ohtomo…
• 关键词：Axillary lymph node dissection ; Breast cancer ; Sentinel lymph node
• 刊名：Breast Cancer
• 出版年：2015
• 出版时间：November 2015
• 年：2015
• 卷：22
• 期：6
• 页码：657-663
• 全文大小：381 KB
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• 作者单位：Reiko Kobayashi (1)
  Kenshiro Shiraishi (1)
  Satoru Iwase (2)
  Kuni Ohtomo (1)
  Keiichi Nakagawa (1)
  
  1. Department of Radiology, University of Tokyo Hospital, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan
  2. Department of Palliative Medicine, Research Hospital, The Institute of Medical Science, The University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan
  
• 刊物主题：Surgical Oncology; Oncology; Surgery; Cancer Research;
• 出版者：Springer Japan
• ISSN：1880-4233

文摘

Background For clinically node negative (N0) breast cancer patients, sentinel node (SN) biopsy (SNB) is a standard technique and complete axillary lymph node dissection (ALND) remains the standard treatment when the SN is positive. However, the American College of Surgeons Oncology Group Z0011 trial and the International Breast Cancer Study Group 23-01 trial showed that SNB without ALND can offer excellent regional control and equal survival compared with ALND for limited macrometastatic and micrometastatic SN involvement, respectively. We retrospectively evaluated axillary control rates in clinically N0 patients who had no axillary surgical treatment.