Human Milk is the Feeding Strategy to Prevent Necrotizing Enterocolitis

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• 作者：Richard J. Schanler (1) (2)
  
• 关键词：Human milk ; Donor human milk ; Necrotizing enterocolitis
• 刊名：Current Pediatrics Reports
• 出版年：2014
• 出版时间：December 2014
• 年：2014
• 卷：2
• 期：4
• 页码：264-268
• 全文大小：153 KB
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• 作者单位：Richard J. Schanler (1) (2)
  
  1. Division of Neonatal-Perinatal Medicine, Cohen Children鈥檚 Medical Center of New York, 269-01 76th Avenue, New Hyde Park, NY, 11040, USA
  2. Hofstra North Shore-LIJ School of Medicine, New Hyde Park, NY, USA
  
• ISSN：2167-4841

文摘

The use of human milk in the neonatal intensive care unit clearly has short and long-term beneficial effects, but its role in the prevention of necrotizing enterocolitis (NEC) cannot be understated. Immaturity of the intestinal tract, barrier function, and mucosal defense contributes to NEC. Human milk feeding enhances maturity of the intestinal tract, barrier functions, and mucosal defenses by providing components such as immunoglobulin A, lactoferrin, lysozyme, oligosaccharides, epidermal growth factor, acetylhydrolase, erythropoietin, arginine and glutamine, and polyunsaturated fatty acids, and the ability to promote a commensal intestinal microflora.