Sealing of Polyester Prostheses with Autologous Fibrin Glue and Bone Marrow

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• 作者：Alain Cardon ; Nabil Chakf¨¦ ; Fabien Thaveau ; Edith Gagnon ; Olivier Hartung ; Sylvie Aillet ; Yvon Kerdiles ; Yves-Marie Dion ; Jean-Georges Kretz and Charles J. Doillon
• 刊名：Annals of Vascular Surgery
• 出版年：2000
• 出版时间：November 2000
• 年：2000
• 卷：14
• 期：6
• 页码：543-552
• 全文大小：1,210 KB

文摘

= 12), sealing with autologous fibrin glue (group II, n= 14), and sealing with autologous fibrin glue and bone marrow cells (group III, n= 16). Feasibility and quality of sealing were evaluated by scanning electron microscopy prior to implantation and by assessment of blood loss. After removal, prostheses were cut into three segments comprising the proximal anastomosis, midsection, and distal anastomosis. Pieces were fixed, embedded in paraffin, and serially sectioned for histologic study. Histological study focused on the degree of stenosis and hyperplasia of the neointima of each prosthesis. The results of this short-term study indicate that sealing of polyester vascular prosthetic grafts with autologous fibrin glue and bone marrow cells is effective in reducing intimal hyperplasia. However further study will be needed to assess long-term healing.