"One-step" bone marrow-derived cells transplantation and joint debridement for osteochondral lesions of the talus in ankle osteoarthritis: clinical and radiological outcomes at 36 months

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• 作者：Roberto Buda ; Francesco Castagnini…
• 关键词：Ankle osteoarthritis ; Osteochondral lesions of the talus ; Bone marrow ; derived cells transplantation ; One step
• 刊名：Archives of Orthopaedic and Trauma Surgery
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：136
• 期：1
• 页码：107-116
• 全文大小：1,402 KB
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• 作者单位：Roberto Buda (1)
  Francesco Castagnini (2)
  Marco Cavallo (2)
  Laura Ramponi (2)
  Francesca Vannini (2)
  Sandro Giannini (1)
  
  1. Orthopedics and Traumatology, I Clinic, Rizzoli Orthopedic Institute, University of Bologna, Bologna, Italy
  2. I Clinic, Rizzoli Orthopedic Institute, Via Pupilli 1, 40136, Bologna, Italy
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Orthopedics
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1434-3916

文摘

Introduction Ankle osteoarthritis (OA) is a challenging pathology, often requiring surgical treatments. In young patients, joint sparing, biologic procedures would be desirable. Recently, a few reports have described the efficacy of bone marrow stem cells in OA. Considering the good outcomes of one-step bone marrow derived cells transplantation (BMDCT) for osteochondral lesions of the talus (OLT), we applied this procedure for OLT in concomitant ankle OA.