The Netherlands protocol for standardisation and quantification of FDG whole body PET studies in multi-centre trials
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- 作者：Ronald Boellaard ; Wim J. G. Oyen ; Corneline J. Hoekstra ; Otto S. Hoekstra ; Eric P. Visser ; Antoon T. Willemsen ; Bertjan Arends ; Fred J. Verzijlbergen ; Josee Zijlstra and Anne M. Paans ; et al.
- 关键词：Standardisation ; FDG ; PET ; Multi ; centre trials ; QC ; SUV ; Quantification
- 刊名：European Journal of Nuclear Medicine and Molecular Imaging
- 出版年：2008
- 出版时间：December, 2008
- 年：2008
- 卷：35
- 期：12
- 页码：2320-2333
- 全文大小：284.1 KB
文摘
Introduction Several studies have shown the usefulness of positron emission tomography (PET) quantification using standardised uptake values (SUV) for diagnosis and staging, prognosis and response monitoring. Many factors affect SUV, such as patient preparation procedures, scan acquisition, image reconstruction and data analysis settings, and the variability in methodology across centres prohibits exchange of SUV data. Therefore, standardisation of 2-[18F] fluoro-2-deoxy-D-glucose (FDG) PET whole body procedures is required in multi-centre trials.