Red-fleshed Apples: Old Autochthonous Fruits as a Novel Source of Anthocyanin Antioxidants

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• 作者：Shadab Faramarzi ; Severina Pacifico ; Abbas Yadollahi…
• 关键词：Iranian red ; fleshed apples ; Radical scavenging activity ; Antioxidant activity ; Cytoprotection ; Anthocyanins
• 刊名：Plant Foods for Human Nutrition
• 出版年：2015
• 出版时间：September 2015
• 年：2015
• 卷：70
• 期：3
• 页码：324-330
• 全文大小：393 KB
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• 作者单位：Shadab Faramarzi (1)
  Severina Pacifico (2)
  Abbas Yadollahi (1)
  Annamaria Lettieri (2)
  Paola Nocera (2)
  Simona Piccolella (2)
  
  1. Department of Horticultural Science, Tarbiat Modares University, Tehran, Iran
  2. Department of Environmental Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Via Vivaldi 43, I-81100, Caserta, Italy
  
• 刊物主题：Food Science; Chemistry/Food Science, general; Nutrition; Ecology; Plant Physiology;
• 出版者：Springer US
• ISSN：1573-9104

文摘

In order to promote breeding programs and a full reintroduction into production of two local red-fleshed apple varieties grown in Bekran and Bastam (Iran), the evaluation of their antioxidant properties was of interest. LC-MSn based metabolic fingerprinting analyses were applied to investigate the anthocyanin content of both peel and flesh components of the fruits. Cyanidin-3-O-hexoside isomers were present in both 鈥楤ekran鈥?and 鈥楤astam鈥?apples, whereas 鈥楤ekran鈥?apple was a valuable source of anthocyanin rutinose derivatives. Employing DPPH鈥?/sup>, ABTS鈥?, and ORAC methods, the antiradical efficacy was evaluated. The ability of the investigated fruit components to scavenge OH鈥?/sup>, and O2 鈥? reactive species was also assessed. ID50 values highlighted the massive antioxidant response of 鈥楤ekran鈥?peel component, able to counteract by 50聽% OH鈥?/sup>, and O2 鈥? at 130.3 and 91.6聽渭g/mL, respectively. The cytoprotective screening towards HeLa, HepG2, A549, SH-5YSY, and SK-N-BE(2)-C cell lines evidenced that the investigated Iranian red-fleshed apple fruits were able to exert a significant antioxidant response in hydrogen peroxide oxidized cell systems. Data collected suggested that the revaluation of 鈥楤ekran鈥?and 鈥楤astam鈥?apple cultivars could represent a precious source of antioxidant compounds whose dietary intake could improve the human well-being reducing risks of free radical related chronic and degenerative diseases.