Preventative Sleeve Gastrectomy Contributes to Maintaining β Cell Function in db/db Diabetic Mouse
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- 作者：Feng Li ; Chunjun Sheng ; Kexiu Song ; Manna Zhang ; Le Bu ; Peng Yang…
- 关键词：Sleeve gastrectomy ; Pancreatic β cell ; Islet ; Transcript factor ; GLP ; 1
- 刊名：Obesity Surgery
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：26
- 期：10
- 页码：2402-2410
- 全文大小：5,724 KB
- 刊物主题：Surgery;
- 出版者：Springer US
- ISSN：1708-0428
- 卷排序：26
文摘
BackgroundWe used the leptin-receptor (LPR)-deficient mice model (db/db), a spontaneous model of type 2 diabetes with early β cell dysfunction to determine whether a preventative sleeve gastrectomy (SG) is an effective technique for the treatment of β cell failure.