Variation of Antioxidant Activity in Dreissena polymorpha Specimens Exposed to 2,2-4,4-5,6-Hexa BDE (BDE-154)
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  • 作者：Marco Parolini (1) marco.parolini@unimi.it
    Alessandra Pedriali (1)
    Andrea Binelli (1)
  • 关键词：2 ; 2′ ; 4 ; 4′ ; 5 ; 6′ ; Hexa BDE (BDE ; 154) – Antioxidant enzymes – Zebra mussel
  • 刊名：Water, Air, and Soil Pollution
  • 出版年：2012
  • 出版时间：July 2012
  • 年：2012
  • 卷：223
  • 期：6
  • 页码：3067-3076
  • 全文大小：373.0 KB
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  • 作者单位：1. Department of Biology, University of Milan, Via Celoria 26, 20133 Milan, Italy
  • 刊物类别：Earth and Environmental Science
  • 刊物主题：Environment
    Environment
    Atmospheric Protection, Air Quality Control and Air Pollution
    Waste Water Technology, Water Pollution Control, Water Management and Aquatic Pollution
    Terrestrial Pollution
    Hydrogeology
  • 出版者：Springer Netherlands
  • ISSN：1573-2932
文摘
We evaluated the imbalance of the oxidative status in zebra mussel (Dreissena polymorpha) specimens exposed for 96 h to environmentally relevant concentrations (0.1, 0.5, and 1 μg/L) of the 2,2′,4,4′,5,6′-hexa BDE (BDE-154). The activities of three antioxidant enzymes, catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx), and the phase II detoxifying enzyme glutathione S-transferase (GST), were measured in the cytosolic fraction from a pool of zebra mussels. Significant variations in the activity of each single enzyme were noticed at each treatment, indicating that exposure to BDE-154 was able to impair the oxidative status of treated bivalves through the increase of reactive oxygen species. In detail, SOD and GPx were significantly induced, while CAT and GST were depressed with respect to the baseline levels. These data have confirmed that the raise of oxidative stress is the main cause of the BDE-154-induced genetic damage observed in a previous study on the zebra mussel.

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