Acknowledging gray areas: 2015 vs. 2009 American Thyroid Association differentiated thyroid cancer guidelines on ablating putatively low-intermediate-risk patients

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• 作者：Savvas Frangos ; Ioannis P. Iakovou…
• 关键词：Differentiated thyroid cancer management guidelines ; 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer ; 2009 revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer ; Thyroid remnant ablation ; Decision ; making ; Recommendations
• 刊名：European Journal of Nuclear Medicine and Molecular Imaging
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：44
• 期：2
• 页码：185-189
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Nuclear Medicine; Imaging / Radiology; Orthopedics; Cardiology; Oncology;
• 出版者：Springer Berlin Heidelberg
• ISSN：1619-7089
• 卷排序：44

文摘

PurposeTypically formulated by investigators from “world centres of excellence,” differentiated thyroid carcinoma (DTC) management guidelines may have more limited applicability in settings of less expert care and fewer resources. Arguably the world’s leading DTC guidelines are those of the American Thyroid Association, revised in 2009 (“ATA 2009”) and 2015 (“ATA 2015”). To further explore the issue of “real-world applicability” of DTC guidelines, we retrospectively compared indications for ablation using ATA 2015 versus ATA 2009 in a two-centre cohort of ablated T1–2, M0 DTC patients (N = 336). Based on TNM status and histology, these patients were low–intermediate risk, but many ultimately had other characteristics suggesting elevated or uncertain risk.