Protection from experimental autoimmune encephalomyelitis by polyclonal IgG requires adjuvant-induced inflammation
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- 作者：Isaak Quast ; Christian W. Keller ; Patrick Weber…
- 关键词：Intravenous immunoglobulin ; Experimental autoimmune encephalomyelitis ; Multiple sclerosis ; T cell ; Dendritic cell ; Innate immunity ; Adjuvant ; Mycobacteria
- 刊名：Journal of Neuroinflammation
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：13
- 期：1
- 全文大小：1,427 KB
- 刊物主题：Neurosciences; Neurology; Neurobiology; Immunology;
- 出版者：BioMed Central
- ISSN：1742-2094
文摘
Background Intravenous immunoglobulin (IVIG) proved to be an efficient anti-inflammatory treatment for a growing number of neuroinflammatory diseases and protects against the development of experimental autoimmune encephalomyelitis (EAE), a widely used animal model for multiple sclerosis (MS).