Risk of chemotherapy-induced febrile neutropenia in cancer patients receiving pegfilgrastim prophylaxis: does timing of administration matter?

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• 作者：Derek Weycker ; Xiaoyan Li ; Jacqueline Figueredo ; Rich Barron…
• 关键词：Febrile neutropenia ; Pegfilgrastim ; Neulasta ; Granulocyte colony ; stimulating factor
• 刊名：Supportive Care in Cancer
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：24
• 期：5
• 页码：2309-2316
• 全文大小：360 KB
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Oncology
  Nursing
  Nursing Management and Research
  Pain Medicine
  Rehabilitation Medicine
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1433-7339

文摘

Purpose Contrary to the approved indication for pegfilgrastim prophylaxis, some patients receive it on the same day as the last administration of chemotherapy in clinical practice, which could adversely impact risk of febrile neutropenia (FN). An evaluation of the timing of pegfilgrastim prophylaxis and FN risk was undertaken.