Multimodality imaging of penile cancer: what radiologists need to know

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• 作者：Chong Hyun Suh (1)
  Akshay D. Baheti (2) (3)
  Sree Harsha Tirumani (2) (3)
  Michael H. Rosenthal (2) (3)
  Kyung Won Kim (1)
  Nikhil H. Ramaiya (2) (3)
  Atul B. Shinagare (2) (3)
  
  1. Department of Radiology and Research Institute of Radiology ; Asan Medical Center ; University of Ulsan College of Medicine ; 88 Olympic-ro 43-gil ; Songpa-gu ; Seoul ; 138-736 ; Korea
  2. Department of Imaging ; Dana Farber Cancer Institute ; Harvard Medical School ; 450 Brookline Avenue ; Boston ; MA ; 02215 ; USA
  3. Department of Radiology ; Brigham and Women鈥檚 Hospital ; Harvard Medical School ; 75 Francis Street ; Boston ; MA ; 02115 ; USA
  
• 关键词：Penile cancer ; 2010 AJCC TNM staging ; Role of imaging ; Management
• 刊名：Abdominal Imaging
• 出版年：2015
• 出版时间：February 2015
• 年：2015
• 卷：40
• 期：2
• 页码：424-435
• 全文大小：2,260 KB
• 参考文献：1. Siegel R, Naishadham D, Jemal A (2012) Cancer statistics, 2012. CA Cancer J Clin 62:10鈥?9 CrossRef
  2. Narayana AS, Olney LE, Loening SA, Weimar GW, Culp DA (1982) Carcinoma of the penis: analysis of 219 cases. Cancer 49:2185鈥?191 CrossRef
  3. Ornellas AA, Seixas AL, Marota A, et al. (1994) Surgical treatment of invasive squamous cell carcinoma of the penis: retrospective analysis of 350 cases. J Urol 151:1244鈥?249
  4. Bleeker MC, Heideman DA, Snijders PJ, et al. (2009) Penile cancer: epidemiology, pathogenesis and prevention. World J Urol 27:141鈥?50 CrossRef
  5. Pow-Sang MR, Ferreira U, Pow-Sang JM, Nardi AC, Destefano V (2010) Epidemiology and natural history of penile cancer. Urology 76:S2鈥揝6 CrossRef
  6. Pow-Sang MR, Benavente V, Pow-Sang JE, et al. (2002) Cancer of the penis. Cancer Control 9:305鈥?14
  7. Daling JR, Madeleine MM, Johnson LG, et al. (2005) Penile cancer: importance of circumcision, human papillomavirus and smoking in in situ and invasive disease. Int J Cancer 116:606鈥?16 CrossRef
  8. Dillner J, von Krogh G, Horenblas S, Meijer CJ (2000) Etiology of squamous cell carcinoma of the penis. Scand J Urol Nephrol Suppl 205:189鈥?93 CrossRef
  9. Sarkar FH, Miles BJ, Plieth DH, Crissman JD (1992) Detection of human papillomavirus in squamous neoplasm of the penis. J Urol 147:389鈥?92
  10. Hernandez BY, Barnholtz-Sloan J, German RR, et al. (2008) Burden of invasive squamous cell carcinoma of the penis in the United States, 1998鈥?003. Cancer 113:2883鈥?891 CrossRef
  11. Horenblas S (2001) Lymphadenectomy for squamous cell carcinoma of the penis. Part 1: diagnosis of lymph node metastasis. BJU Int 88:467鈥?72 CrossRef
  12. Eble JN, Sauter G, Epstein JI, Sesterhenn I, World Health Organization Classification of Tumours (2004) / Pathology and genetics of tumours of the urinary system and male genital organs. Lyon: IARC Press
  13. Cubilla AL, Reuter V, Velazquez E, et al. (2001) Histologic classification of penile carcinoma and its relation to outcome in 61 patients with primary resection. Int J Surg Pathol 9:111鈥?20 CrossRef
  14. Horenblas S, van Tinteren H (1994) Squamous cell carcinoma of the penis. IV. Prognostic factors of survival: analysis of tumor, nodes and metastasis classification system. J Urol 151:1239鈥?243
  15. Horenblas S, Van Tinteren H, Delemarre JF, et al. (1991) Squamous cell carcinoma of the penis: accuracy of tumor, nodes and metastasis classification system, and role of lymphangiography, computerized tomography scan and fine needle aspiration cytology. J Urol 146:1279鈥?283
  16. Edge SBBD, Compton CC, et al. (2010) / AJCC Cancer Staging Manual, 7th edn. New York: Springer, pp 447鈥?51
  17. Petralia G, Villa G, Scardino E, et al. (2008) Local staging of penile cancer using magnetic resonance imaging with pharmacologically induced penile erection. Radiol Med (Torino) 113:517鈥?28 CrossRef
  18. Clark P, Spiess P, Agarwal N, et al. Penile cancer Version 1.2014. National Comprehensive Cancer Network Web-site. penile.pdf" class="a-plus-plus">www.nccn.org/professionals/physician_gls/pdf/penile.pdf. Accessed April 27, 2014
  19. Singh AK, Saokar A, Hahn PF, Harisinghani MG (2005) Imaging of penile neoplasms. Radiographics 25:1629鈥?638 CrossRef
  20. Kayes O, Minhas S, Allen C, et al. (2007) The role of magnetic resonance imaging in the local staging of penile cancer. Eur Urol 51:1313鈥?318 ((discussion 1318鈥?319)) CrossRef
  21. Lont AP, Besnard AP, Gallee MP, van Tinteren H, Horenblas S (2003) A comparison of physical examination and imaging in determining the extent of primary penile carcinoma. BJU Int 91:493鈥?95 CrossRef
  22. Leijte JA, Horenblas S (2009) Shortcomings of the current TNM classification for penile carcinoma: time for a change? World J Urol 27:151鈥?54 CrossRef
  23. Ravi R (1993) Correlation between the extent of nodal involvement and survival following groin dissection for carcinoma of the penis. Br J Urol 72:817鈥?19 CrossRef
  24. Catalona WJ (1988) Modified inguinal lymphadenectomy for carcinoma of the penis with preservation of saphenous veins: technique and preliminary results. J Urol 140:306鈥?10
  25. McDougal WS (1995) Carcinoma of the penis: improved survival by early regional lymphadenectomy based on the histological grade and depth of invasion of the primary lesion. J Urol 154:1364鈥?366 CrossRef
  26. Kroon BK, Horenblas S, Lont AP, et al. (2005) Patients with penile carcinoma benefit from immediate resection of clinically occult lymph node metastases. J Urol 173:816鈥?19 CrossRef
  27. Solsona E, Algaba F, Horenblas S, Pizzocaro G, Windahl T (2004) EAU guidelines on penile cancer. Eur Urol 46:1鈥? CrossRef
  28. Schlenker B, Scher B, Tiling R, et al. (2012) Detection of inguinal lymph node involvement in penile squamous cell carcinoma by 18F-fluorodeoxyglucose PET/CT: a prospective single-center study. Urol Oncol 30:55鈥?9 CrossRef
  29. Graafland NM, Leijte JA, Valdes Olmos RA, et al. (2009) Scanning with 18F-FDG-PET/CT for detection of pelvic nodal involvement in inguinal node-positive penile carcinoma. Eur Urol 56:339鈥?45 CrossRef
  30. Sadeghi R, Gholami H, Zakavi SR, Kakhki VR, Horenblas S (2012) Accuracy of 18F-FDG PET/CT for diagnosing inguinal lymph node involvement in penile squamous cell carcinoma: systematic review and meta-analysis of the literature. Clin Nucl Med 37:436鈥?41 CrossRef
  31. Tabatabaei S, Harisinghani M, McDougal WS (2005) Regional lymph node staging using lymphotropic nanoparticle enhanced magnetic resonance imaging with ferumoxtran-10 in patients with penile cancer. J Urol 174:923鈥?27 ((discussion 927)) CrossRef
  32. Ornellas AA, Kinchin EW, Nobrega BL, et al. (2008) Surgical treatment of invasive squamous cell carcinoma of the penis: Brazilian National Cancer Institute long-term experience. J Surg Oncol 97:487鈥?95 CrossRef
  33. Rippentrop JM, Joslyn SA, Konety BR (2004) Squamous cell carcinoma of the penis: evaluation of data from the surveillance, epidemiology, and end results program. Cancer 101:1357鈥?363 CrossRef
  34. Lopes A, Bezerra AL, Serrano SV, Hidalgo GS (2000) Iliac nodal metastases from carcinoma of the penis treated surgically. BJU Int 86:690鈥?93 CrossRef
  35. Pow-Sang JE, Benavente V, Pow-Sang JM, Pow-Sang M (1990) Bilateral ilioinguinal lymph node dissection in the management of cancer of the penis. Semin Surg Oncol 6:241鈥?42 CrossRef
  36. Ravi R (1993) Morbidity following groin dissection for penile carcinoma. Br J Urol 72:941鈥?45 CrossRef
  37. Sanchez-Ortiz RF, Pettaway CA (2004) The role of lymphadenectomy in penile cancer. Urol Oncol 22:236鈥?44 ((discussion 244鈥?35)) CrossRef
  38. Srinivas V, Morse MJ, Herr HW, Sogani PC, Whitmore WF Jr (1987) Penile cancer: relation of extent of nodal metastasis to survival. J Urol 137:880鈥?82
  39. Saisorn I, Lawrentschuk N, Leewansangtong S, Bolton DM (2006) Fine-needle aspiration cytology predicts inguinal lymph node metastasis without antibiotic pretreatment in penile carcinoma. BJU Int 97:1225鈥?228 CrossRef
  40. Heyns CF, Fleshner N, Sangar V, et al. (2010) Management of the lymph nodes in penile cancer. Urology 76:S43鈥揝57 CrossRef
  41. Sadeghi R, Gholami H, Zakavi SR, et al. (2012) Accuracy of sentinel lymph node biopsy for inguinal lymph node staging of penile squamous cell carcinoma: systematic review and meta-analysis of the literature. J Urol 187:25鈥?1 CrossRef
  42. Spiess PE, Izawa JI, Bassett R, et al. (2007) Preoperative lymphoscintigraphy and dynamic sentinel node biopsy for staging penile cancer: results with pathological correlation. J Urol 177:2157鈥?161 CrossRef
  43. Culkin DJ, Beer TM (2003) Advanced penile carcinoma. J Urol 170:359鈥?65 CrossRef
  44. Pagliaro LC, Williams DL, Daliani D, et al. (2010) Neoadjuvant paclitaxel, ifosfamide, and cisplatin chemotherapy for metastatic penile cancer: a phase II study. J Clin Oncology 28:3851鈥?857 CrossRef
  45. Theodore C, Skoneczna I, Bodrogi I, et al. (2008) A phase II multicentre study of irinotecan (CPT 11) in combination with cisplatin (CDDP) in metastatic or locally advanced penile carcinoma (EORTC PROTOCOL 30992). Ann Oncol 19:1304鈥?307 CrossRef
  46. Haas GP, Blumenstein BA, Gagliano RG, et al. (1999) Cisplatin, methotrexate and bleomycin for the treatment of carcinoma of the penis: a Southwest Oncology Group study. J Urol 161:1823鈥?825 CrossRef
  47. Pettaway CA, Pagliaro L, Theodore C, Haas G (2010) Treatment of visceral, unresectable, or bulky/unresectable regional metastases of penile cancer. Urology 76:S58鈥揝65 CrossRef
  48. Crook JM, Jezioranski J, Grimard L, Esche B, Pond G (2005) Penile brachytherapy: results for 49 patients. Int J Radiat Oncol Biol Phys 62:460鈥?67 CrossRef
  49. Zouhair A, Coucke PA, Jeanneret W, et al. (1990) Radiation therapy alone or combined surgery and radiation therapy in squamous-cell carcinoma of the penis? Eur J Cancer 2001(37):198鈥?03
  50. Azrif M, Logue JP, Swindell R, et al. (2006) External-beam radiotherapy in T1鈥? N0 penile carcinoma. Clin Oncol (R Coll Radiol) 18:320鈥?25 CrossRef
  51. de Crevoisier R, Slimane K, Sanfilippo N, et al. (2009) Long-term results of brachytherapy for carcinoma of the penis confined to the glans (N- or NX). Int J Radiat Oncol Biol Phys 74:1150鈥?156 CrossRef
  52. Leijte JA, Kirrander P, Antonini N, Windahl T, Horenblas S (2008) Recurrence patterns of squamous cell carcinoma of the penis: recommendations for follow-up based on a two-centre analysis of 700 patients. Eur Urol 54:161鈥?68 CrossRef
  53. Chaux A, Reuter V, Lezcano C, et al. (2009) Comparison of morphologic features and outcome of resected recurrent and nonrecurrent squamous cell carcinoma of the penis: a study of 81 cases. Am J Surg Pathol 33:1299鈥?306 CrossRef
  54. Ornellas AA, Nobrega BL, Wei Kin Chin E, et al. (2008) Prognostic factors in invasive squamous cell carcinoma of the penis: analysis of 196 patients treated at the Brazilian National Cancer Institute. J Urol 180:1354鈥?359 CrossRef
  55. Graafland NM, Moonen LM, van Boven HH, et al. (2011) Inguinal recurrence following therapeutic lymphadenectomy for node positive penile carcinoma: outcome and implications for management. J Urol 185:888鈥?93 CrossRef
  
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Imaging and Radiology
  Gastroenterology
  Hepatology
  
• 出版者：Springer New York
• ISSN：1432-0509

文摘

The purpose of this article is to provide a comprehensive update on the role of imaging in the diagnosis and management of penile cancer. Imaging plays a major role in the initial assessment, treatment planning, and follow-up of patients with penile carcinoma. MRI helps in assessing the T staging of the primary and in detecting local recurrence. PET/CT and CT are useful for detecting regional nodal and distant metastases.