Diagnose und Behandlung der perinatalen Asphyxie
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- 作者：PD Dr. A. Hilgendorff (1)
- 关键词：Neugeborenes ; Asphyxie ; Hypoxisch ; isch?mische Enzephalopathie ; überwachung ; Hypothermie ; Infant ; newborn ; Asphyxia ; Hypoxic ; ischemic encephalopathy ; Monitoring ; Hypothermia
- 刊名：Monatsschrift Kinderheilkunde
- 出版年：2014
- 出版时间：November 2014
- 年：2014
- 卷：162
- 期：11
- 页码：1033-1045
- 全文大小：703 KB
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1. Perinatalzentrum Gro?hadern, Dr. von Haunersches Kinderspital, Klinikum der Ludwig-Maximilians-Universit?t München, Marchioninistra?e 15, 81377, München, Deutschland- ISSN：1433-0474
- 作者单位：PD Dr. A. Hilgendorff (1)
文摘
Perinatal asphyxia has its origin at the time of delivery and is defined as the presence of severe metabolic acidosis with a pH ?.0 and a base deficit ?12?mmol/l in an arterial blood sample taken immediately after birth in association with organ dysfunction. The most severe complication following neonatal asphyxia is the development of hypoxic-ischemic encephalopathy. The application of controlled hypothermia aims at reducing the risk of long-term sequelae arising from this complication and should be performed according to the recommendations of large clinical trials by a specialized perinatal center. As the presence of distinct criteria and imaging results are of prognostic value, monitoring of these patients should include these diagnostics and documentation of the respective clinical variables. Long-term follow-up of neurologic development are recommended.