Chronic Inflammatory Bowel Disease as Key Manifestation of Atypical ARTEMIS Deficiency
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- 作者：Jan Rohr ; Ulrich Pannicke ; Michaela D?ring ; Annette Schmitt-Graeff ; Elisabeth Wiech ; Andreas Busch ; Carsten Speckmann ; Ingo M¨¹ller ; Peter Lang and Rupert Handgretinger ; et al.
- 关键词：Inflammatory bowel disease ; lymphopenia ; primary immunodeficiency ; Artemis
- 刊名：Journal of Clinical Immunology
- 出版年：2010
- 出版时间：March, 2010
- 年：2010
- 卷：30
- 期：2
- 页码：314-320
- 全文大小：324.6 KB
文摘
Introduction We describe a girl presenting at age 6 years with a history of chronic ulcerating intestinal inflammation since 9 months of age. She exhibited a severe, steroid-dependent clinical course of intestinal inflammation over several years in the absence of serious infections.