Mechanical competence of bone-implant systems can accurately be determined by image-based micro-finite element analyses

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• 作者：Andreas J. Wirth ; Thomas L. Mueller ; Wim Vereecken ; Cyril Flaig ; Peter Arbenz ; Ralph M¨¹ller and G. Harry van Lenthe
• 关键词：Bone ; implant competence ; Micro ; finite element analysis (μ ; FEA) ; Bone microstructure ; Peri ; implant bone quality ; Mechanical testing ; Pull ; out strength
• 刊名：Archive of Applied Mechanics (Ingenieur Archiv)
• 出版年：2010
• 出版时间：May, 2010
• 年：2010
• 卷：80
• 期：5
• 页码：513-525
• 全文大小：555.3 KB

文摘

The precise failure mechanisms of bone implants are still incompletely understood. Micro-computed tomography in combination with finite element analysis appears to be a potent methodology to determine the mechanical stability of bone-implant constructs. To assess this microstructural finite element (μFE) analysis approach, pull-out tests were designed and conducted on ten sheep vertebral bodies into which orthopedic screws were inserted. μFE models of the same bone-implant constructs were then built and solved, using a large-scale linear FE-solver. μFE calculated pull-out strength correlated highly with the experimentally measured pull-out strength (r 2 = 0.87) thereby statistically supporting the μFE approach. These results suggest that bone-implant constructs can be analyzed using μFE in a detailed and unprecedented way. This could potentially facilitate the development of future implant designs leading to novel and improved fracture fixation methods.