Bioactivity and Bioavailability of Ginsenosides are Dependent on the Glycosidase Activities of the A/J Mouse Intestinal Microbiome Defined by Pyrosequencing

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• 作者：Tao Niu (1)
  Diane L. Smith (2)
  Zhen Yang (1)
  Song Gao (1)
  Taijun Yin (1)
  Zhi-Hong Jiang (3)
  Ming You (4)
  Richard A. Gibbs (5)
  Joseph F. Petrosino (6)
  Ming Hu (1)
  
• 关键词：16S rRNA gene sequencing ; F2 and C ; K ; ginseng ; ginsenosides Rb1 ; microbiome ; permeability ; pharmacokinetic profile ; rate ; limiting step ; Rd ; stepwise metabolism
• 刊名：Pharmaceutical Research
• 出版年：2013
• 出版时间：March 2013
• 年：2013
• 卷：30
• 期：3
• 页码：836-846
• 全文大小：506KB
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• 作者单位：Tao Niu (1)
  Diane L. Smith (2)
  Zhen Yang (1)
  Song Gao (1)
  Taijun Yin (1)
  Zhi-Hong Jiang (3)
  Ming You (4)
  Richard A. Gibbs (5)
  Joseph F. Petrosino (6)
  Ming Hu (1)
  
  1. Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, 1441 Moursund Street, Houston, Texas, 77030, USA
  2. Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, 77030, USA
  3. School of Chinese Medicine, Hong Kong Baptist University, 7 Baptist University Road, Kowloon Tong, Hong Kong
  4. Medical College of Wisconsin Cancer Center, 8701 West Watertown Plank Road, Milwaukee, Wisconsin, 53226, USA
  5. Human Genome Sequencing Center, Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, 77030, USA
  6. Alkek Center for Metagenomics and Microbiome Research Department of Molecular Virology and Microbiology, Human Genome Sequencing Center, Baylor College of Medicine, One Baylor Plaza, Houston, Texas, 77030, USA
  
• ISSN：1573-904X

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