Oxidative Damage and Cytotoxicity of Perfluorooctane Sulfonate on Chlorella vulgaris

详细信息    查看全文

• 作者：Dongmei Xu ; Xuesong Chen ; Bo Shao
• 关键词：PFOS ; Algae ; Antioxidant defense systems ; Cell permeability ; Chlorophyll
• 刊名：Bulletin of Environmental Contamination and Toxicology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：98
• 期：1
• 页码：127-132
• 全文大小：
• 刊物主题：Pollution, general; Environmental Health; Ecotoxicology; Soil Science & Conservation; Environmental Chemistry; Waste Water Technology / Water Pollution Control / Water Management / Aquatic Pollution;
• 出版者：Springer US
• ISSN：1432-0800
• 卷排序：98

文摘

We studied the effects of perfluorooctane sulfonate (PFOS) on the chlorophyll content, cell permeability, and antioxidant defense systems of the green alga Chlorella vulgaris. The results showed that the production of reactive oxygen species increased in a concentration-dependent manner after exposure to PFOS for 96 h. Superoxide dismutase and catalase activity was elevated after exposure to the lower concentrations and then decreased with higher concentrations. Malondialdehyde content was significantly higher than that of controls at the higher PFOS concentrations. Cell membrane permeability increased. These results indicate that PFOS exposure leads to oxidative damage in C. vulgaris. At these concentrations, chlorophyll and the structure of chloroplasts were destroyed.