Latest Developments in Cognitive Functioning in Mood and Anxiety Disorders

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• 作者：Felicia Gould ; Sara Kaplan ; Philip D. Harvey
• 关键词：Cognition ; Depression ; Anxiety ; PTSD ; Bipolar ; MDD
• 刊名：Current Behavioral Neuroscience Reports
• 出版年：2015
• 出版时间：September 2015
• 年：2015
• 卷：2
• 期：3
• 页码：165-172
• 全文大小：285KB
• 参考文献：1.Keefe RS, McClintock SM, Roth RM, Doraiswamy PM, Tiger S, Madhoo M. Cognitive effects of pharmacotherapy for major depressive disorder: a systematic review. J Clin Psychiatry. 2014;75:864鈥?6.
  2.McIntyre RS, Lophaven S, Olsen CK. A randomized, double-blind, placebo-controlled study of vortioxetine on cognitive function in depressed adults. Int J Neuropsychopharmacol. 2014;17:1557鈥?7.PubMed Central PubMed CrossRef
  3.Mcintyre RS, Cha DS, Soczynska JK, Woldeyohannes HO, Gallaugher LA, Kudlow P, et al. Cognitive deficits and functional outcomes in major depressive disorder: determinants, substrates, and treatment interventions. Depress Anxiety. 2013;30:515鈥?7.PubMed CrossRef
  4.Lam RW, Kennedy SH, McIntyre RS, Khullar A. Cognitive dysfunction in major depressive disorder: effects on psychosocial functioning and implications for treatment. Can J Psychiatry. 2014;59:649鈥?4.PubMed Central PubMed
  5.Harvey PD, Bellack AS. Toward a terminology of functional recovery in schizophrenia: is functional remission a viable concept? Schizophr Bull. 2009;35:300鈥?.PubMed Central PubMed CrossRef
  6.McIntyre RS, Soczynska JZ, Woldeyohannes HO, Alsuwaidan MT, Cha DS, Carvalho AF, et al. The impact of cognitive impairment on perceived workforce performance: results from the international mood disorders collaborative project. Compr Psychiatry. 2015;56:279鈥?2.PubMed CrossRef
  7.Harvey PD, Pinkham AE. Impaired self-assessment in schizophrenia: why patients misjudge their cognition and functioning. Curr Psychiatry. 2015;14:53鈥?.
  8.Mausbach BT, Harvey PD, Goldman SR, Jeste DV, Patterson TL. Development of a brief scale of everyday functioning in persons with serious mental illness. Schizophr Bull. 2007;33:1364鈥?2.PubMed Central PubMed CrossRef
  9.Day CV, Gatt JM, Etkin A, DeBattista C, Schatzberg AF, Williams LM. Cognitive and emotional biomarkers of melancholic depression: an iSPOT-D report. J Affect Disord. 2015;176:141鈥?0.PubMed CrossRef
  10.Mahableshwarkar AR, Zajecka J, Jacobson W, Chen Y, Keefe Richard SE. A randomized, placebo-controlled, active-reference, double-blind, flexible-dose study of the efficacy of vortioxetine on cognitive function in major depressive disorder. Neuropsychopharmacology. 2015;1鈥?3.
  11.Katona C, Hansen T, Olsen CK. A randomized, double-blind, placebo-controlled, duloxetine-referenced, fixed-dose study comparing the efficacy and safety of Lu AA21004 in elderly patients with major depressive disorder. Int Clin Psychopharmacol. 2012;27:215鈥?3.PubMed CrossRef
  12.Madhoo M, Keefe Richard SE, Roth RM, Sambunaris A, Wu J, Trivedi MH, et al. Lisdexamfetamine dimesylate augmentation in adults with persistent executive dysfunction after partial or full remission of major depressive disorder. Neuropsychopharmacology. 2014;39:1388鈥?8.PubMed Central PubMed CrossRef
  13.Groves SJ, Porter RJ, Jordan J, Knight R, Carter JD, McIntosh Virginia VW, Fernando K, Frampton Christopher MA, Mulder RT, Lacey C, Joyce PR. Changes in neuropsychological function after treatment with metacognitive therapy or cognitive behavior therapy for depression. Depress Anxiety. 2015:1鈥?.
  14.Harvey PD, Wingo AP, Burdick KE, Baldessarini RJ. Cognition and disability in bipolar disorder: lessons from schizophrenia research. Bipolar Disord. 2010;12:364鈥?5.PubMed CrossRef
  15.Bowie CR, Holshausen K, Gupta M. Comparative impairments across schizophrenia and bipolar disorder. In: Harvey PD, editor. Cognitive impairments in schizophrenia. New York: Cambridge University Press; 2013. p. 50鈥?8.
  16.Keefe Richard SE, Fox KH, Davis VG, Kennel C, Walker TM, Burdick KE, et al. The brief assessment of cognition in affective disorders (BAC-A): performance of patients with bipolar depression and healthy controls. J Affect Disord. 2014;166:86鈥?2.PubMed CrossRef
  17.Bauer IE, Keefe RS, Sanches M, Suchting R, Green CE, Soares JC. Evaluation of cognitive function in bipolar disorder using the Brief Assessment of Cognition in Affective Disorders (BAC-A). J Psychiatry Res. 2015;60:80鈥?.CrossRef
  18.Bowie CR, Depp C, McGrath JA, Wolyniec P, Mausbach BT, Thornquist MH, et al. Prediction of real world functional disability in chronic mental disorders: a comparison of schizophrenia and bipolar disorder. Am J Psychiatry. 2010;167:1116鈥?4.PubMed Central PubMed CrossRef
  19.Harvey PD, Siever LJ, Huang GD, Muralidhar S, Zhao H, Miller P, et al. The genetics of functional disability in schizophrenia and bipolar illness: methods and initial results for VA comparative study #572. Am J Med Genet Part B. 2014;165B:381鈥?.PubMed CrossRef
  20.Harvey PD, Paschall G, Depp C. Factors influencing self-assessment of cognition and functioning in bipolar disorder: a preliminary study. Cogn Neuropsychiatry. 2015;20:361鈥?1.PubMed CrossRef
  21.Silveira LE, Kozicky J, Muralidharan K, Bucker J, Torres IJ, Bond DJ, et al. Neurocognitive functioning in overweight and obese patients with bipolar disorder: data from the systematic treatment optimization program for early mania (STOP-EM). Can J Psychiatry. 2014;59:639鈥?8.PubMed Central PubMed
  22.Depp CA, Strassnig M, Mausbach BT, Bowie CR, Wolyniec P, Thornquist MH, et al. Association of obesity and treated hypertension and diabetes with cognitive ability in bipolar disorder and schizophrenia. Bipolar Disord. 2014;16:422鈥?1.PubMed Central PubMed CrossRef
  23.Depp CA, Bowie CR, Mausbach BT, Wolyniec P, Thornquist MH, Luke JR, McGrath JA, Pulver AE, Patterson TL, Harvey PD. Current smoking is associated with worse cognitive and adaptive functioning in serious mental illness. Acta Psychiatr Scand. 2015:1鈥?.
  24.Kaye JL, Dunlop BW, Iosifescu DV, Mathew SJ, Kelley ME, Harvey PD. Cognition, functional capacity, and self-reported disability in women with posttraumatic stress disorder: examining the convergence of performance-based measures and self-reports. J Psychiatr Res. 2014;57:51鈥?.
  25.Twamley EW, Allard CB, Thorp SR, Norman SB, Hami Cissel S, Hughes Berardi K, et al. Cognitive impairment and functioning in PTSD related to intimate partner violence. J Int Neuropsychol Soc. 2009;15:879鈥?7.PubMed CrossRef
  26.Suliman S, Stein DJ, Seedat S. Clinical and neuropsychological predictors of posttraumatic stress disorder. Medicine (Baltimore). 2014;93:e113.CrossRef
  27.Marin MF, Lonak SF, Milad MR. Augmentation of evidence-based psychotherapy for PTSD with cognitive enhancers. Curr Psychiatry Rep. 2015;17:582.CrossRef
  
• 作者单位：Felicia Gould (1)
  Sara Kaplan (1)
  Philip D. Harvey (1) (2)
  
  1. Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 1450, Miami, FL, 33136, USA
  2. Research Service, Miami VA Medical Center, Miami, FL, USA
  
• 刊物类别：Psychiatry; Behavioral Therapy; Neurology; Pediatrics;
• 刊物主题：Psychiatry; Behavioral Therapy; Neurology; Pediatrics;
• 出版者：Springer International Publishing
• ISSN：2196-2979

文摘

Cognitive impairments are well-documented features of mood and anxiety disorders. Recent developments in research on cognition, assessment techniques, treatments, and comorbidities in cognitive changes across major depression, bipolar disorder, and post-traumatic stress disorder (PTSD) are reviewed. Promising treatments have been reported but are tempered by self-reported cognitive performance and its minimal relationship to objective data. The need for objective assessment as well as assessment of subjective impressions of cognition is discussed. The use of assessment of performance-based measures of everyday functional skills in major depression, bipolar disorder, and PTSD is another critical development highlighted in the present review. The recent success of pharmacological treatments for cognitive impairments in major depressive disorder (MDD) is promising, yet the need for clinicians to assess and consider bias in their treatment outcome data is essential. Keywords Cognition Depression Anxiety PTSD Bipolar MDD