CANABIC: CANnabis and Adolescents: effect of a Brief Intervention on their Consumption -study protocol for a randomized controlled trial
详细信息 查看全文
- 作者：Catherine Laporte (15) (16)
Hélène Vaillant-Roussel (15)
Bruno Pereira (17)
Olivier Blanc (15) (18)
Gilles Tanguy (15)
Paul Frappé (19)
David Costa (20)
Yoann Gaboreau (21)
Mélanie Badin (20)
Laurent Marty (15) (22)
Gilles Clément (15)
Claude Dubray (23)
Bruno Falissard (24)
Pierre-Michel Llorca (18)
Philippe Vorilhon (15) (25) - 关键词：Adolescents and young adults ; Brief intervention ; Cannabis ; General medicine
- 刊名：Trials
- 出版年：2014
- 出版时间：December 2014
- 年：2014
- 卷：15
- 期：1
- 全文大小：361 KB
- 作者单位：Catherine Laporte (15) (16)
Hélène Vaillant-Roussel (15)
Bruno Pereira (17)
Olivier Blanc (15) (18)
Gilles Tanguy (15)
Paul Frappé (19)
David Costa (20)
Yoann Gaboreau (21)
Mélanie Badin (20)
Laurent Marty (15) (22)
Gilles Clément (15)
Claude Dubray (23)
Bruno Falissard (24)
Pierre-Michel Llorca (18)
Philippe Vorilhon (15) (25)
15. Department of General Medicine, Faculty of Medicine of Clermont-Ferrand, 28 Place Henri Dunant, 63000, Clermont-Ferrand, France
16. EA 7280 NPsy-Sydo, Faculty of Medicine of Clermont-Ferrand, University of Auvergne, 28 Place Henri Dunant, 63000, Clermont-Ferrand, France
17. Office for Clinical Research and Innovation, Clermont-Ferrand University Hospital, 58 Rue Montalembert, 63000, Clermont-Ferrand, France
18. Adult Psychiatry Department -B, Clermont-Ferrand University Hospital, 58 Rue Montalembert, 63000, Clermont-Ferrand, France
19. Department of General Medicine, Saint-Etienne Faculty of Medicine, 15 Rue Ambroise Paré, 42023, St Etienne Cedex 2, France
20. Department of General Medicine, Montpellier Faculty of Medicine, 2 Rue de l’école de Médecine, 34000, Montpellier, France
21. Department of General Medicine, Grenoble Faculty of Medicine, Domaine de la Merci, BP 170 La Tronche, 38042, Grenoble Cedex 9, France
22. Health anthropologist, 7 rue de l’église, 63450, St Amant Tallende, France
23. Clinical Investigation Centre (Inserm CIC -501), Clermont-Ferrand University Hospital, 58 Rue Montalembert, 63000, Clermont-Ferrand, France
24. Faculty of Medicine, Paris South, INSERM 669 Unit, Maison de Solenn, 97 Bld de Port Royal, 75679, Paris cedex 14, France
25. EA 4681PEPRADE, Faculty of Medicine of Clermont-Ferrand, University of Auvergne, 28 Place Henri Dunant, 63000, Clermont-Ferrand, France - ISSN：1745-6215
文摘
Background Cannabis is the most consumed illegal substance in France. General practitioners (GPs) are the health professionals who are most consulted by adolescents. Brief intervention (BI) is a promising care initiative for the consumption of cannabis, and could be a tool for GPs in caring for adolescents who consume cannabis. The aim of the CANABIC study is to measure the impact of a BI carried out by a GP on the consumption of cannabis by adolescents of 15 to 25?years of age. Methods A randomized clustered controlled trial, stratified over three areas (Auvergne, Languedoc-Roussillon, and Rh?ne - Alpes), comparing an intervention group, which carries out the BI in consultation, and a control group, which ensures routine medical care. The main assessment criterion is the consumption of cannabis by amount of joints per month, at 12?months. The amount necessary to highlight a significant difference between the two groups of 30% of consumption at 12?months is 250 patients (50 GPs, 5 patients per GP; risk α--%; power--0%; intra-cluster correlation coefficient ρ--.2; Hawthorne effect--5%; lost to follow-up rates for GPs--0% and for patients--0%). This plan is replicated for the three areas, and therefore a total of 750 patients are expected. The secondary criteria for judgment are the associated consumption of tobacco and alcohol, the perception of the consequences of consumption, and the driving of a vehicle following consumption. Discussion Research about BI for young cannabis users is underway. The aim of the CANABIC study is to validate a BI suited to adolescents who consume cannabis, which may be performed in the general practice. This would provide a tool for their treatment by a GP, which could be widely distributed during initial or further medical training. Trial registration CANABIC is a randomized clustered trial (NCT01433692, registered 2011 Sept 12), PHRC funded: Clinical Research Hospital Program (Governmental Fund, Health Ministry). Date first patient randomized: March 2012.