Synthesis of ethriolophospholipids of acetal type

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• 作者：G. A. Savin
• 关键词：acetal ; type phospholipids ; amidophosphites ; 2 ; hydroxymethyl ; 2 ; ethyl ; 1 ; 3 ; propanediol ; phospholipids thioanalogues
• 刊名：Russian Journal of Bioorganic Chemistry
• 出版年：2006
• 出版时间：September, 2006
• 年：2006
• 卷：32
• 期：5
• 页码：504-505
• 全文大小：144 KB
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Biochemistry
  Bioorganic Chemistry
  Organic Chemistry
  Biomedicine
  Russian Library of Science
  
• 出版者：MAIK Nauka/Interperiodica distributed exclusively by Springer Science+Business Media LLC.
• ISSN：1608-330X

文摘

New analogues of acetal-type phospholipids were obtained on the basis of ethriol (2-hydroxymethy1-2-ethyl-1,3-propanediol). The starting triol originally was condensed with decanal or dodecanal to form acetals, which were then phosphorylated with tetraethyldiamidophosphorous acid chloride. The amidophosphites were further oxidized with iodosobenzene or sulfurized to the corresponding acetal-type phospholipids and their thio analogues.