Ocular higher-order aberration features 10years after photorefractive keratectomy

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• 作者：Lin Zhang (1)
  Yan Wang (2)
  Weili Geng (1)
  Tong Zuo (1)
  Ying Jin (1)
  Xiaoyan Yang (1)
  Lu Wang (1)
  
• 关键词：Photorefractive keratectomy ; Long ; term follow ; up ; Higher ; order aberration ; Optical quality ; Myopia
• 刊名：International Ophthalmology
• 出版年：2013
• 出版时间：December 2013
• 年：2013
• 卷：33
• 期：6
• 页码：651-657
• 全文大小：
• 作者单位：Lin Zhang (1)
  Yan Wang (2)
  Weili Geng (1)
  Tong Zuo (1)
  Ying Jin (1)
  Xiaoyan Yang (1)
  Lu Wang (1)
  
  1. Tianjin Eye Hospital & Eye Institute, Tianjin Medical University, No 4. Gansu Rd, Heping District, Tianjin, 300020, China
  2. Tianjin Eye Hospital & Eye Institute, Ophthalmology and Visual Development Key Laboratory, Tianjin Medical University, No 4. Gansu Rd, Heping District, Tianjin, 300020, China
  
• ISSN：1573-2630

文摘

The aim of the present study is to re-evaluate the original cohort of patients who participated in the first photorefractive keratectomy (PRK) trial in the 1990s, especially their optical performance. Forty-four eyes (24 patients) of the original cohort who underwent PRK using the NIDK EC-5000 excimer laser platform returned 10years (range 94years) postoperatively to have higher-order aberrations (HOAs) recorded. Wavefront aberrations were measured using Wavescan (VISX, Santa Clara, CA, USA) and calculated for 3- and 6-mm pupil size. The total RMS (the square root of the sum of squared Zernike coefficients) of higher-order wavefront error (3rdth radial order) and the Zernike coefficients, as well as the third-order (S 3) and fourth-order (S 4) aberrations, spherical aberrations and coma aberration values were analyzed. An independent sample t test was used for comparisons and a P value<0.05 was considered statistically significant. The mean RMS of higher-order wavefront values showed an increase but no significant difference in postoperative eyes compared to the control-matched normal level with the 6-mm pupil (HOA RMS: control group 0.310.12; 10-year post-PRK group 0.560.15; P=0.141). The main contribution was the increase of spherical aberrations (Z 12) and spherical-like aberrations (S 4), which increased by fourfold and 2.5-fold, respectively, in the 10-year post-PRK group (control group Z 12 0.080.11, S 4 0.140.05; 10-year post-PRK group Z 12 0.350.15, S 4 0.370.14; P=0.010*). Most increases of ocular HOAs induced by corneal refractive surgery are becoming extremely minor at 10years postoperatively, closer to the corresponding preoperative amount. The largest increase was spherical and spherical-like aberrations, especially with a larger pupil size.