Phytochemical studies for quantitative estimation of iridoid glycosides in Picrorhiza kurroa Royle
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- 作者：Phalisteen Sultan ; Arif Jan ; Qazi Pervaiz
- 关键词：Picroside ; Apocyanin ; Cucurbitacin ; Accessions ; Chromatography ; Iridoid ; Herbal
- 刊名：Botanical Studies
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：57
- 期：1
- 全文大小：1,102 KB
- 刊物主题：Plant Sciences;
- 出版者：Springer Berlin Heidelberg
- ISSN：1999-3110
文摘
Background Picrorhiza kurroa Royle commonly known as ‘Kutki or Kutaki’ is an important medicinal plant in Ayurvedic system of medicine and has traditionally been used to treat disorders of the liver and upper respiratory tract. The plant is the principle source of iridoid glycosides, picrosides I, II and kutkoside used in various herbal drug formulations mainly as strong hepatoprotective and immune-modulatory compound. The species has become endangered to near extinction due to the unregulated collection from the wild, slower plant growth and ecological destruction of natural habitats. There is a severe shortage of plant material, while the market demand is ever increasing. Hence, it is very important to apply a simple and precise analytical method to determine and validate the concentration of the major bioactive constituents in different populations of this plant species for development of a high yielding chemotype for large scale production and its commercial exploitation on scientific lines.