Einfluss der CMD auf die mechanische Schmerzschwelle au?erhalb der Kopf-Gesichts-Region
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文摘
Background and objective There is currently no evidence of changes in pressure sensitivity of myofascial trigger points (MTrPs) in extra-trigeminal regions in patients with craniomandibular dysfunction (CMD). The purpose of this study was to evaluate whether pressure sensitivity of MTrPs in patients with CMD increases in trigeminal and extra-trigeminal regions compared to a healthy control group. Furthermore, the extent to which MTrPs can be used as diagnostic markers for hyperalgesia in patients with CMD was investigated. Subjects and methods In this study 34 patients with CMD (15-4 years old) and 30 healthy control subjects (22-5 years old) were included. The pressure pain threshold of MTrPs in trigeminal and extra-trigeminal regions was measured and compared. Additionally, the most suitable diagnostic marker of hyperalgesia in patients with CMD was investigated using ROC curve analysis. Results Pressure sensitivity of all MTrPs was significantly increased in the CMD group. Even after correction for multiple testing, most of the effects continued to be significant. The trapezius muscle was the most suitable among all MTrPs for the classification of hyperalgesia in patients with CMD. Assuming a false positive rate of below 5-, 42- of patients with CMD were classified as hyperalgetic. Discussion The significant differences in pressure sensitivity of MTrPs in trigeminal and extra-trigeminal regions indicate that hyperalgesia is present in patients with CMD. The trapezius muscle might be a marker for diagnosing hyperalgesia. Further studies are required in order to identify gender and age-specific indicators.

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