Detectability of Fast Ripples (>250 Hz) on the Scalp EEG: A Proof-of-Principle Study with Subdermal Electrodes

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• 作者：Francesca Pizzo ; Birgit Frauscher ; Taissa Ferrari-Marinho ; Mina Amiri…
• 关键词：Fast ripples ; Scalp EEG ; Subdermal electrodes ; Focal epilepsy ; High frequency oscillations
• 刊名：Brain Topography
• 出版年：2016
• 出版时间：May 2016
• 年：2016
• 卷：29
• 期：3
• 页码：358-367
• 全文大小：856 KB
• 参考文献：Akiyama T, McCoy B, Go CY, Ochi A, Elliott IM, Akiyama M et al (2011) Focal resection of fast ripples on extraoperative intracranial EEG improves seizure outcome in pediatric epilepsy. Epilepsia 52(10):1802–1811CrossRef PubMed
  Alkawadri R, Gaspard N, Goncharova II, Spencer DD, Gerrard JL, Zaveri H et al (2014) The spatial and signal characteristics of physiologic high frequency oscillations. Epilepsia 55(12):1986–1995. doi:10.​1111/​epi.​12851 CrossRef PubMed
  Andrade-Valenca LP, Dubeau F, Mari F, Zelmann R, Gotman J (2011) Interictal scalp fast oscillations as a marker of the seizure onset zone. Neurology 77(6):524–531CrossRef PubMed PubMedCentral
  Bagshaw AP, Jacobs J, Levan P, Dubeau F, Gotman J (2009) Effect of sleep stage on interictal high-frequency oscillations recorded from depth macroelectrodes in patients with focal epilepsy. Epilepsia 50(4):617–628CrossRef PubMed PubMedCentral
  Bénar CG, Chauvière L, Bartolomei F, Wendling F (2010) Pitfalls of high-pass filtering for detecting epileptic oscillations: a technical note on “false” ripples. Clin Neurophysiol 121(3):301–310. doi:10.​1016/​j.​clinph.​2009.​10.​019 CrossRef PubMed
  Berry RB, Brooks R, Gamaldo CE, Harding SM, Marcus CL, Vaughn BV (2012) The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications, version 2.0. American Academy of Sleep Medicine, Darien. http://​www.​aasmnet.​org
  Blanco JA, Stead M, Krieger A, Stacey W, Maus D, Marsh E et al (2011) Data mining neocortical high-frequency oscillations in epilepsy and controls. Brain 134(10):2948–2959CrossRef PubMed PubMedCentral
  Bragin A, Engel J, Wilson CL, Fried I, Buzsáki G (1999a) High-frequency oscillations in human brain. Hippocampus 9(2):137–142CrossRef PubMed
  Bragin A, Engel J, Wilson CL, Fried I, Mathern GW (1999b) Hippocampal and entorhinal cortex high-frequency oscillations (100–500 Hz) in human epileptic brain and in kainic acid-treated rats with chronic seizures. Epilepsia 40(2):127–137CrossRef PubMed
  Bragin A, Wilson CL, Engel J (2000) Chronic epileptogenesis requires development of a network of pathologically interconnected neuron clusters: a hypothesis. Epilepsia 41(Suppl 6):S144–S152CrossRef PubMed
  Crépon B, Navarro V, Hasboun D, Clemenceau S, Martinerie J, Baulac M et al (2010) Mapping interictal oscillations greater than 200 Hz recorded with intracranial macroelectrodes in human epilepsy. Brain 133(1):33–45CrossRef PubMed
  Curio G (2000) Linking 600-Hz “spikelike” EEG/MEG wavelets (“σ-bursts”) to cellular substrates. J Clin Neurophysiol 17:377–396CrossRef PubMed
  Dümpelmann M, Jacobs J, Schulze-Bonhage A (2015) Temporal and spatial characteristics of high frequency oscillations as a new biomarker in epilepsy. Epilepsia 56(2):197–206. doi:10.​1111/​epi.​12844 CrossRef PubMed
  Foffani G, Uzcategui YG, Gal B, Menendez de la Prida L (2007) Reduced spike-timing reliability correlates with the emergence of fast ripples in the rat epileptic hippocampus. Neuron 55(6):930–941CrossRef PubMed
  Frauscher B, von Ellenrieder N, Ferrari-Marinho T, Avoli M, Dubeau F, Gotman J (2015) Facilitation of epileptic activity during sleep is mediated by high amplitude slow waves. Brain 138:1629–1641. doi:10.​1093/​brain/​awv073 CrossRef PubMed PubMedCentral
  Gobbelé R, Waberski TD, Simon H, Peters E, Klostermann F, Curio G et al (2004) Different origins of low- and high-frequency components (600 Hz) of human somatosensory evoked potentials. Clin Neurophysiol 115(4):927–937CrossRef PubMed
  Ibarz JM, Foffani G, Cid E, Inostroza M, Menendez de la Prida L (2010) Emergent dynamics of fast ripples in the epileptic hippocampus. J Neurosci 30(48):16249–16261CrossRef PubMed
  Ives JR (2005) New chronic EEG electrode for critical/intensive care unit monitoring. J Clin Neurophysiol 22(2):119–123CrossRef PubMed
  Iwatani Y, Kagitani-Shimono K, Tominaga K, Okinaga T, Kishima H, Kato A et al (2012) Ictal high-frequency oscillations on scalp EEG recordings in symptomatic West syndrome. Epilepsy Res 102(1–2):60–70. doi:10.​1016/​j.​eplepsyres.​2012.​04.​020 CrossRef PubMed
  Jacobs J, LeVan P, Chander R, Hall J, Dubeau F, Gotman J (2008) Interictal high-frequency oscillations (80–500 Hz) are an indicator of seizure onset areas independent of spikes in the human epileptic brain. Epilepsia 49(11):1893–1907CrossRef PubMed PubMedCentral
  Jirsch JD, Urrestarazu E, LeVan P, Olivier A, Dubeau F, Gotman J (2006) High-frequency oscillations during human focal seizures. Brain 129(6):1593–1608CrossRef PubMed
  Kerber K, Dümpelmann M, Schelter B, Le Van P, Korinthenberg R, Schulze-Bonhage A et al (2014) Differentiation of specific ripple patterns helps to identify epileptogenic areas for surgical procedures. Clin Neurophysiol 125(7):1339–1445. doi:10.​1016/​j.​clinph.​2013.​11.​030 CrossRef PubMed
  Kobayashi K, Watanabe Y, Inoue T, Oka M, Yoshinaga H, Ohtsuka Y (2010) Scalp-recorded high-frequency oscillations in childhood sleep-induced electrical status epilepticus. Epilepsia 51(10):2190–2194CrossRef PubMed
  Kobayashi K, Yoshinaga H, Toda Y, Inoue T, Oka M, Ohtsuka Y (2011) High-frequency oscillations in idiopathic partial epilepsy of childhood. Epilepsia 52(10):1812–1819CrossRef PubMed
  Kobayashi K, Akiyama T, Oka M, Endoh F, Yoshinaga H (2015) A storm of fast (40–150 Hz) oscillations during hypsarrhythmia in West syndrome. Ann Neurol 77:58–67CrossRef PubMed
  Kucewicz MT, Cimbalnik J, Matsumoto JY, Brinkmann BH, Bower MR, Vasoli V et al (2014) High frequency oscillations are associated with cognitive processing in human recognition memory. Brain 137(8):2231–2244CrossRef PubMed PubMedCentral
  Matsumoto A, Brinkmann BH, Matthew Stead S, Matsumoto J, Kucewicz MT, Marsh WR et al (2013) Pathological and physiological high-frequency oscillations in focal human epilepsy. J Neurophysiol 110(8):1958–1964CrossRef PubMed PubMedCentral
  Melani F, Zelmann R, Dubeau F, Gotman J (2013) Occurrence of scalp-fast oscillations among patients with different spiking rate and their role as epileptogenicity marker. Epilepsy Res 106(3):345–356CrossRef PubMed PubMedCentral
  Miao A, Xiang J, Tang L, Ge H, Liu H, Wu T et al (2014) Using ictal high-frequency oscillations (80–500 Hz) to localize seizure onset zones in childhood absence epilepsy: a MEG study. Neurosci Lett 566:21–26. doi:10.​1016/​j.​neulet.​2014.​02.​038 CrossRef PubMed
  Schevon CA, Trevelyan AJ, Schroeder CE, Goodman RR, McKhann G, Emerson RG (2009) Spatial characterization of interictal high frequency oscillations in epileptic neocortex. Brain 132(11):3047–3059CrossRef PubMed PubMedCentral
  Staba RJ, Wilson CL, Bragin A, Fried I, Engel J (2002) Quantitative analysis of high-frequency oscillations (80–500 Hz) recorded in human epileptic hippocampus and entorhinal cortex. J Neurophysiol 88(4):1743–1752PubMed
  Staba RJ, Wilson CL, Bragin A, Jhung D, Fried I, Engel J Jr (2004) High-frequency oscillations recorded in human medial temporal lobe during sleep. Ann Neurol 56:108–115CrossRef PubMed
  Staley KJ (2007) Neurons skip a beat during fast ripples. Neuron 55(6):828–830CrossRef PubMed
  Tao JX, Ray A, Hawes-Ebersole S, Ebersole JS (2005) Intracranial EEG substrates of scalp EEG interictal spikes. Epilepsia 46(5):669–676CrossRef PubMed
  Urrestarazu E, Chander R, Dubeau F, Gotman J (2007) Interictal high-frequency oscillations (100–500 Hz) in the intracerebral EEG of epileptic patients. Brain 130(9):2354–2366CrossRef PubMed
  Van Klink NEC, van’t Klooster MA, Zelmann R, Leijten FSS, Ferrier CH, Braun KPJ et al (2014) High frequency oscillations in intra-operative electrocorticography before and after epilepsy surgery. Clin Neurophysiol 125(11):2212–2219. doi:10.​1016/​j.​clinph.​2014.​03.​004 CrossRef PubMed
  Von Ellenrieder N, Beltrachini L, Perucca P, Gotman J (2014) Size of cortical generators of epileptic interictal events and visibility on scalp EEG. Neuroimage 94:47–54. doi:10.​1016/​j.​neuroimage.​2014.​02.​032 CrossRef
  Worrell GA, Gardner AB, Stead SM, Hu S, Goerss S, Cascino GJ et al (2008) High-frequency oscillations in human temporal lobe: simultaneous microwire and clinical macroelectrode recordings. Brain 131(4):928–937CrossRef PubMed PubMedCentral
  Wu JY, Sankar R, Lerner JT, Matsumoto JH, Vinters HV, Mathern GW (2010) Removing interictal fast ripples on electrocorticography linked with seizure freedom in children. Neurology. 75(19):1686–1694CrossRef PubMed PubMedCentral
  Zelmann R, Lina JM, Schulze-Bonhage A, Gotman J, Jacobs J (2014) Scalp EEG is not a blur: it can see high frequency oscillations although their generators are small. Brain Topogr 27(5):683–704CrossRef PubMed
  
• 作者单位：Francesca Pizzo (1) (2)
  Birgit Frauscher (1)
  Taissa Ferrari-Marinho (1) (3)
  Mina Amiri (1)
  Francois Dubeau (1)
  Jean Gotman (1)
  
  1. Montreal Neurological Institute and Hospital, McGill University, Montreal, QC, Canada
  2. Epilepsy Unit, Careggi Hospital, University of Florence, Florence, Italy
  3. Department of Clinical Neurophysiology, Hospital Israelita Albert Einstein, São Paulo, Brazil
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Biomedicine
  Neurosciences
  Psychiatry
  Neurology
  
• 出版者：Springer New York
• ISSN：1573-6792

文摘

To evaluate the possibility of detecting fast ripples (FRs) on the surface EEG of patients with focal pharmacoresistant epilepsy, and to investigate the relationship between scalp FRs and localization of the seizure onset zone (SOZ). We included 10 patients undergoing combined surface–intracranial EEG with ≥10 spikes in the surface EEG during the first 30 consecutive minutes of N3 sleep. FRs (≥4 consecutive oscillations above 250 Hz with an amplitude clearly exceeding that of the background) on the surface EEG (F3-C3, C3-P3, Fz-Cz, Cz-Pz, F4-C4, C4-P4) were visually marked, and verified by two EEG experts. FRs were categorized as related to the SOZ, if localized in the brain lobe of the SOZ. Low-amplitude FRs with a rate of 0.09/min were found in 6/10 patients: two exhibited events related to the SOZ, three showed no relationship with the SOZ, and in one patient the SOZ was not identified. It may be possible to detect FRs with surface EEG using subdermal electrodes in patients with focal epilepsy. The relationship between surface FRs and the SOZ remains unclear. Future studies aiming at a higher spatial EEG coverage are needed to elucidate their significance.