Fiducial markers for image-guided partial breast irradiation

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• 作者：Marco Trovo (1)
  Jerry Polesel (2)
  Cristina Biasutti (1)
  Giovanna Sartor (3)
  Mario Roncadin (1)
  Gaetano Mauro Trovo (1)
  
• 关键词：Image ; guided radiation therapy ; Partial breast irradiation ; Fiducial markers ; Radioterapia guidata dalle immagini ; Irradiazione parziale della mammella ; Marcatori fiduciali
• 刊名：La radiologia medica
• 出版年：2013
• 出版时间：October 2013
• 年：2013
• 卷：118
• 期：7
• 页码：1212-1219
• 全文大小：
• 作者单位：Marco Trovo (1)
  Jerry Polesel (2)
  Cristina Biasutti (1)
  Giovanna Sartor (3)
  Mario Roncadin (1)
  Gaetano Mauro Trovo (1)
  
  1. Department of Radiation Oncology, Centro di Riferimento Oncologico, CRO, Via F. Gallini 2, 33081, Aviano (PN), Italy
  2. Department of Epidemiology and Biostatistics, Centro di Riferimento Oncologico, CRO, Aviano (PN), Italy
  3. Department of Medical Physics, Centro di Riferimento Oncologico, CRO, Aviano (PN), Italy
  
• ISSN：1826-6983

文摘

Purpose This study was undertaken to study the role of fiducial markers for image-guided partial breast irradiation (IG-PBI), and to compare the shifts based on bony anatomy and fiducial markers. Materials and methods Fifteen patients underwent IGPBI. Three fiducial markers were placed in the tumour bed at the time of surgery. Daily orthogonal anterior/ posterior and lateral kV-images were taken before each fraction and compared with the digitally-reconstructed radiographs, both using bony landmarks and fiducial markers as reference. The Student’s t test was used to detect a meaningful difference of 3 mm in between the two methods. Results A total of 105 image-guided radiation therapy (IGRT) sessions were obtained. The mean superior/inferior, right/left, and anterior/posterior shifts obtained using the bony landmarks vs. the fiducial markers were 2 mm [standard deviation (SD) 10 mm] vs. 0 mm (SD 7 mm), 0 mm (SD 7 mm) vs. 1 mm (SD 4 mm), and 1 mm (SD 7 mm) vs. 0 mm (SD 5 mm), respectively. The mean shift differences in absolute value between the two methods, along the superior/inferior, right/left and anterior/posterior directions were 5 mm (p=0.001), 3 mm [p=not significant (ns)], and 3 mm (p=ns), respectively. Conclusions Fiducial markers for IG-PBI increase set-up accuracy compared to the bony landmarks, in particular along the superior/inferior direction.