Chemopreventive Potential of Resveratrol in Mouse Skin Tumors Through Regulation of Mitochondrial and PI3K/AKT Signaling Pathways

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• 作者：Preeti Roy ; Neetu Kalra ; Sahdeo Prasad ; Jasmine George and Yogeshwer Shukla
• 关键词：KEY WORDS apoptosis ; chemoprevention ; mouse skin tumorigenesis ; PI3K/AKT pathway ; resveratrol
• 刊名：Pharmaceutical Research
• 出版年：2009
• 出版时间：January, 2009
• 年：2009
• 卷：26
• 期：1
• 页码：211-217
• 全文大小：277.8 KB

文摘

Purpose To investigate the chemopreventive potential of resveratrol, a phytoalexin found in seeds and skin of grapes, berries and peanuts in 7,12 dimethyl benz(a)anthracene (DMBA) induced mouse skin tumorigenesis.