The diagnostic value of CRP, IL-8, PCT, and sTREM-1 in the detection of bacterial infections in pediatric oncology patients with febrile neutropenia

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• 作者：Karin G. E. Miedema (1) k.g.e.miedema@bkk.umcg.nl
  Eveline S. J. M. de Bont (1)
  Rob F. M. Oude Elferink (2)
  Michel J. van Vliet (1)
  Claudi S. M. Oude Nijhuis (1)
  Willem A. Kamps (1)
  Wim J. E. Tissing (1) w.j.e.tissing@bkk.umcg.nl
• 关键词：Febrile neutropenia &#8211 ; Bacterial infection &#8211 ; Biomarkers &#8211 ; Children &#8211 ; Mucositis
• 刊名：Supportive Care in Cancer
• 出版年：2011
• 出版时间：October 2011
• 年：2011
• 卷：19
• 期：10
• 页码：1593-1600
• 全文大小：246.8 KB
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• 作者单位：1. Division of Pediatric Oncology and Pediatric Hematology, Beatrix Children鈥檚 Hospital, University Medical Center Groningen, University of Groningen, PO Box聽30.001, 9700 RB Groningen, The Netherlands2. Department of Clinical Chemistry and Hematology, Martini Hospital/Lab Noord, Groningen, The Netherlands
• 刊物类别：Medicine
• 刊物主题：Medicine & Public Health
  Oncology
  Nursing
  Nursing Management and Research
  Pain Medicine
  Rehabilitation Medicine
  
• 出版者：Springer Berlin / Heidelberg
• ISSN：1433-7339

文摘

Purpose In this study, we evaluated C-reactive protein (CRP), interleukin (IL)-8, procalcitonin (PCT), and soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) as predictors for bacterial infection in febrile neutropenia, plus their usefulness in febrile neutropenia during chemotherapy-induced gastrointestinal mucositis.