Pregnancy-associated malaria and malaria in infants: an old problem with present consequences
详细信息 查看全文
- 作者：Violeta Moya-Alvarez (18) (19) (20)
Rosa Abellana (21)
Michel Cot (18) (19)
18. Institut de Recherche pour le D茅veloppement ; UMR 216 M猫re et enfant face aux infections tropicales ; Facult茅 de Pharmacie Paris Descartes ; 4 Avenue de l鈥橭bservatoire ; 75270 ; Paris ; France
19. Centre Biom茅dical des Cordeliers ; Universit茅 Pierre et Marie Curie (Paris 6) ; 15 ; rue de l鈥橢cole de M茅decine ; 75006 ; Paris ; France
20. R茅seau doctoral de l鈥橢cole des Hautes Etudes en Sant茅 Publique ; Avenue du Professeur L茅on-Bernard ; CS 74312-35043 ; Rennes ; France
21. Departament de Salut P煤blica ; Facultat de Medicina ; Casanova 143 ; 08036 ; Barcelona ; Spain - 关键词：Pregnancy ; associated malaria ; Immune tolerance ; Intermittent preventive treatment in pregnancy ; Parasitaemia ; Infancy ; Sulphadoxine ; pyrimethamine
- 刊名：Malaria Journal
- 出版年：2014
- 出版时间：December 2014
- 年：2014
- 卷：13
- 期：1
- 全文大小：887 KB
- 参考文献：1. David, PH, Hommel, M, Miller, LH, Udeinya, IJ, Oligino, LD (1983) Parasite sequestration in Plasmodium falciparum malaria: spleen and antibody modulation of cytoadherence of infected erythrocytes. Proc Natl Acad Sci U S A 80: pp. 5075-5079 lass="external" href="http://dx.doi.org/10.1073/pnas.80.16.5075" target="_blank" title="It opens in new window">CrossRef
2. Fried, M, Duffy, PE (1996) Adherence of Plasmodium falciparum to chondroitin sulfate A in the human placenta. Science 272: pp. 1502-1504 lass="external" href="http://dx.doi.org/10.1126/science.272.5267.1502" target="_blank" title="It opens in new window">CrossRef
3. Salanti, A, Staalsoe, T, Lavstsen, T, Jensen, ATR, Sowa, MPK, Arnot, DE, Hviid, L, Theander, TG (2003) Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria. Mol Microbiol 49: pp. 179-191 lass="external" href="http://dx.doi.org/10.1046/j.1365-2958.2003.03570.x" target="_blank" title="It opens in new window">CrossRef
4. Dellicour, S, Tatem, AJ, Guerra, CA, Snow, RW, ter Kuile, FO (2010) Quantifying the number of pregnancies at risk of malaria in 2007: a demographic study. PLoS Med 7: pp. e1000221 lass="external" href="http://dx.doi.org/10.1371/journal.pmed.1000221" target="_blank" title="It opens in new window">CrossRef
World Malaria Report. World Health Organization, Geneva
5. Brabin, BJ (1991) The Risk and Severity of Malaria in Pregnant Women. World Health Organisation publications, Geneva
6. Menendez, C (1995) Malaria during pregnancy : a priority area of malaria research and control. Parasitol Today 11: pp. 178-183 lass="external" href="http://dx.doi.org/10.1016/0169-4758(95)80151-0" target="_blank" title="It opens in new window">CrossRef
7. Nosten, F, Rogerson, SJ, Beeson, JG, Mcgready, R, Mutabingwa, TK, Brabin, B (2004) Malaria in pregnancy and the endemicity spectrum: what can we learn?. Trends Parasitol 20: pp. 425-432 lass="external" href="http://dx.doi.org/10.1016/j.pt.2004.06.007" target="_blank" title="It opens in new window">CrossRef
8. Brabin, BJ, Romagosa, C, Abdelgalil, S, Men茅ndez, C, Verhoeff, FH, McGready, R, Fletcher, KA, Owens, S, D鈥橝lessandro, U, Nosten, F, Fischer, PR, Ordi, J (2004) The sick placenta-the role of malaria. Placenta 25: pp. 359-378 lass="external" href="http://dx.doi.org/10.1016/j.placenta.2003.10.019" target="_blank" title="It opens in new window">CrossRef
9. Desai, M, Kuile, FO, Nosten, F, Mcgready, R, Asamoa, K, Brabin, B, Newman, RD (2007) Epidemiology and burden of malaria in pregnancy. Lancet Infect Dis 7(2): pp. 93-104 lass="external" href="http://dx.doi.org/10.1016/S1473-3099(07)70021-X" target="_blank" title="It opens in new window">CrossRef
10. Rogerson, SJ, Hviid, L, Duff, PE, Leke, RFG, Taylor, DW (2007) Malaria in pregnancy: pathogenesis and immunity. Lancet Infect Dis 7: pp. 105-117 lass="external" href="http://dx.doi.org/10.1016/S1473-3099(07)70022-1" target="_blank" title="It opens in new window">CrossRef
11. Steketee, RW, Nahlen, BL, Parise, ME, Menendez, C (2001) The burden of malaria in pregnancy in malaria-endemic areas. Am J Trop Med Hyg 64: pp. 28-35
12. Le Hesran, J-Y, Cot, M, Personne, P, Fievet, N, Dubois, B, Beyeme, M, Boudin, C, Deloron, P (1997) Maternal placental infection with Plasmodium falciparum and malaria morbidity during the first 2聽years of life. Am J Epidemiol 146: pp. 826-831 lass="external" href="http://dx.doi.org/10.1093/oxfordjournals.aje.a009200" target="_blank" title="It opens in new window">CrossRef
13. Mutabingwa, TK, Bolla, MC, Li, J-L, Domingo, GJ, Li, X, Fried, M, Duffy, PE (2005) Maternal malaria and gravidity interact to modify infant susceptibility to malaria. PLoS Med 2: pp. e407 lass="external" href="http://dx.doi.org/10.1371/journal.pmed.0020407" target="_blank" title="It opens in new window">CrossRef
14. Schwarz, NG, Adegnika, AA, Breitling, LP, Gabor, J, Agnandji, ST, Newman, RD, Lell, B, Issifou, S, Yazdanbakhsh, M, Luty, AJF, Kremsner, PG, Grobusch, MP (2008) Placental malaria increases malaria risk in the first 30聽months of life. Clin Infect Dis 47: pp. 1017-1025 lass="external" href="http://dx.doi.org/10.1086/591968" target="_blank" title="It opens in new window">CrossRef
15. Malhotra, I, Dent, A, Mungai, P, Wamachi, A, Ouma, JH, Narum, DL, Muchiri, E, Tisch, DJ, King, CL (2009) Can prenatal malaria exposure produce an immune tolerant phenotype? A prospective birth cohort study in Kenya. PLoS Med 6: pp. e1000116 lass="external" href="http://dx.doi.org/10.1371/journal.pmed.1000116" target="_blank" title="It opens in new window">CrossRef
16. Le Port, A, Watier, L, Cottrell, G, Oue, S, Pierrat, C, Rachas, A, Bouscaillou, J, Bouraima, A, Massougbodji, A, Chandre, F, Migot-nabias, F, Fayomi, B, Thie, A, Cot, M (2011) Infections in infants during the first 12聽months of life: role of placental malaria and environmental factors. PLoS One 6: pp. e27516 lass="external" href="http://dx.doi.org/10.1371/journal.pone.0027516" target="_blank" title="It opens in new window">CrossRef
17. Tonga, C, Kimbi, HK, Anchang-Kimbi, JK, Nyabeyeu, HN, Bissemou, ZB, Lehman, LG (2013) Malaria risk factors in women on intermittent preventive treatment at delivery and their effects on pregnancy outcome in Sanaga-Maritime, Cameroon. PLoS One 8: pp. e65876 lass="external" href="http://dx.doi.org/10.1371/journal.pone.0065876" target="_blank" title="It opens in new window">CrossRef
World Malaria Report 2013. WHO Publ, Geneva
18. Rachas, A, Le Port, A, Cottrell, G, Guerra, J, Choudat, I, Bouscaillou, J, Massougbodji, A, Garcia, A (2012) Placental malaria is associated with increased risk of nonmalaria infection during the first 18聽months of life in a Beninese population. Clin Infect Dis 55: pp. 672-678 lass="external" href="http://dx.doi.org/10.1093/cid/cis490" target="_blank" title="It opens in new window">CrossRef
19. Slutsker, L, Khoromana, CO, Hightower, AW, Macheso, A, Wirima, JJ, Breman, JG, Heymann, DL, Steketee, RW (1996) Malaria infection in infancy in rural Malawi. Am J Trop Med Hyg 55: pp. 71-76
20. Bardaj铆, A, Sigauque, B, Sanz, S, Maixenchs, M, Ordi, J, Aponte, JJ, Mabunda, S, Alonso, PL, Men茅ndez, C (2011) Impact of malaria at the end of pregnancy on infant mortality and morbidity. J Infect Dis 203: pp. 691-699 lass="external" href="http://dx.doi.org/10.1093/infdis/jiq049" target="_blank" title="It opens in new window">CrossRef
21. Le Port, A, Cottrell, G, Martin-Prevel, Y, Migot-nabias, F, Cot, M (2012) First malaria infections in a cohort of infants in Benin: biological , environmental and genetic determinants: description of the study site , population methods and preliminary results. BMJ Open 2: pp. e000342 lass="external" href="http://dx.doi.org/10.1136/bmjopen-2011-000342" target="_blank" title="It opens in new window">CrossRef
22. Borgella, S, Fievet, N, Huynh, B-T, Ibitokou, S, Hounguevou, G, Affedjou, J, Sagbo, J-C, Houngbegnon, P, Guezo-M茅vo, B, Massougbodji, A, Luty, AJF, Cot, M, Deloron, P (2013) Impact of pregnancy-associated malaria on infant malaria infection in southern Benin. PLoS One 8: pp. e80624 lass="external" href="http://dx.doi.org/10.1371/journal.pone.0080624" target="_blank" title="It opens in new window">CrossRef
23. Falade, C, Mokuolu, O, Okafor, H, Orogade, A, Falade, A, Adedoyin, O, Oguonu, T, Aisha, M, Hamer, DH, Callahan, MV (2007) Epidemiology of congenital malaria in Nigeria: a multi-centre study. Trop Med Int Health 12: pp. 1279-1287 lass="external" href="http://dx.doi.org/10.1111/j.1365-3156.2007.01931.x" target="_blank" title="It opens in new window">CrossRef
24. Vanga-Bosson, H, Coffie, P, Kanhon, S, Sloan, C, Kouakou, F, Eholie, SP, Kone, M, Dabis, F, Menan, H, Ekouevi, DK (2011) Coverage of intermittent prevention treatment with sulphadoxine-pyrimethamine among pregnant women and congenital malaria in C么te d鈥橧voire. Malar J 10: pp. 105 lass="external" href="http://dx.doi.org/10.1186/1475-2875-10-105" target="_blank" title="It opens in new window">CrossRef
25. Omalu, ICJ, Mgbemena, C, Mgbemena, A, Ayanwale, V, Olayemi, IK, Lateef, A, Chukwuemeka, VI (2012) Prevalence of congenital malaria in Minna, north central Nigeria. J Trop Med 2012: pp. 274142 lass="external" href="http://dx.doi.org/10.1155/2012/274142" target="_blank" title="It opens in new window">CrossRef
26. Ou茅draogo, A, Tiono, AB, Diarra, A, Bougouma, ECC, N茅bi茅, I, Konat茅, AT, Sirima, SB (2012) Transplacental transmission of Plasmodium falciparum in a highly malaria endemic area of Burkina Faso. J Trop Med 2012: pp. 109705 lass="external" href="http://dx.doi.org/10.1155/2012/109705" target="_blank" title="It opens in new window">CrossRef
27. Enweronu-Laryea, CC, Adjei, GO, Mensah, B, Duah, N, Quashie, NB (2013) Prevalence of congenital malaria in high-risk Ghanaian newborns: a cross-sectional study. Malar J 12: pp. 17 lass="external" href="http://dx.doi.org/10.1186/1475-2875-12-17" target="_blank" title="It opens in new window">CrossRef
28. Menendez, C, Mayor, A (2007) Congenital malaria: the least known consequence of malaria in pregnancy. Semin Fetal Neonatal Med 12: pp. 207-213 lass="external" href="http://dx.doi.org/10.1016/j.siny.2007.01.018" target="_blank" title="It opens in new window">CrossRef
29. Ibhanesebhor, SE (1995) Clinical characteristics of neonatal malaria. J Trop Pediatr 41: pp. 330-333 lass="external" href="http://dx.doi.org/10.1093/tropej/41.6.330" target="_blank" title="It opens in new window">CrossRef
30. Dechavanne, C, Pierrat, C, Renard, E, Costes, B, Martin, N, Ladekpo, R, Ahouangninou, C, Moya Alvarez, V, Huyn, BT, Garcia, A, Migot-Nabias, F (2013) Genetic characterization of Plasmodium falciparum allelic variants infecting mothers at delivery and their children during their first plasmodial infections. Infect Genet Evol 20: pp. 16-25 lass="external" href="http://dx.doi.org/10.1016/j.meegid.2013.07.026" target="_blank" title="It opens in new window">CrossRef
31. Branch, OH, Udhayakumar, V, Hightower, AW, Oloo, AJ, Hawley, WA, Nahlen, BL, Bloland, PB, Kaslow, DC, Lal, AA (1998) A longitudinal investigation of IgG and IgM antibody responses to the merozoite surface protein-1 19-kiloDalton domain of Plasmodium falciparum in pregnant women and infants: associations with febrile illness, parasitemia, and anemia. Am J Trop Med Hyg 58: pp. 211-219
32. Okoko, BJ, Wesumperuma, LH, Ota, MO, Pinder, M, Banya, W, Gomez, SF, McAdam, KP, Hart, AC (2001) The influence of placental malaria infection and maternal hypergammaglobulinemia on transplacental transfer of antibodies and IgG subclasses in a rural West African population. J Infect Dis 184: pp. 627-632 lass="external" href="http://dx.doi.org/10.1086/322808" target="_blank" title="It opens in new window">CrossRef
33. Riley, EM, Wagner, GE, Akanmori, BD, Koram, KA (2001) Do maternally acquired antibodies protect infants from malaria infection?. Parasite Immunol 23: pp. 51-59 lass="external" href="http://dx.doi.org/10.1046/j.1365-3024.2001.00364.x" target="_blank" title="It opens in new window">CrossRef
34. Brabin, BJ (1983) An analysis of malaria in pregnancy in Africa. Bull World Health Organ 61: pp. 1005-1016
35. Verhoeff, FH, Le Cessie, S, Kalanda, BF, Kazembe, PN, Broadhead, RL, Brabin, BJ (2004) Post-neonatal infant mortality in Malawi: the importance of maternal health. Ann Trop Paediatr 24: pp. 161-169 lass="external" href="http://dx.doi.org/10.1179/027249304225013448" target="_blank" title="It opens in new window">CrossRef
36. Garcia, A, Milet, J, Courtin, D, Sabbagh, A, Massaro, JD, Castelli, EC, Migot-Nabias, F, Favier, B, Rouas-Freiss, N, Donadi, EA, Moreau, P (2013) Association of HLA-G 3鈥睻TR polymorphisms with response to malaria infection: a first insight. Infect Genet Evol 16: pp. 263-269 lass="external" href="http://dx.doi.org/10.1016/j.meegid.2013.02.021" target="_blank" title="It opens in new window">CrossRef
37. Abu-Raddad, LJ, Patnaik, P, Kublin, JG (2006) Dual infection with HIV and malaria fuels the spread of both diseases in sub-Saharan Africa. Science 314: pp. 1603-1606 lass="external" href="http://dx.doi.org/10.1126/science.1132338" target="_blank" title="It opens in new window">CrossRef
38. Ladner, J, Leroy, V, Karita, E, Van de Perre, P, Dabis, F (2003) Malaria, HIV and pregnancy. AIDS 17: pp. 275-276 lass="external" href="http://dx.doi.org/10.1097/00002030-200301240-00025" target="_blank" title="It opens in new window">CrossRef
39. Bulterys, PL, Chao, A, Dalai, SC, Zink, MC, Dushimimana, A, Katzenstein, D, Saah, AJ, Bulterys, M (2011) Placental malaria and mother-to-child transmission of human immunodeficiency virus-1 in rural Rwanda. Am J Trop Med Hyg 85: pp. 202-206 lass="external" href="http://dx.doi.org/10.4269/ajtmh.2011.10-0589" target="_blank" title="It opens in new window">CrossRef
40. Kourtis, AP, Lee, FK (2014) Understanding the timing of HIV. JAMA 285: pp. 18-21
41. Perrault, SD, Hajek, J, Zhong, K, Owino, SO, Sichangi, M, Smith, G, Shi, YP, Moore, JM, Kain, KC (2009) Human immunodeficiency virus co-infection increases placental parasite density and transplacental malaria transmission in Western Kenya. Am J Trop Med Hyg 80: pp. 119-125
42. Van Eijk, AM, Ayisi, JG, ter Kuile, FO, Misore, AO, Otieno, JA, Rosen, DH, Kager, PA, Steketee, RW, Nahlen, BL (2003) HIV increases the risk of malaria in women of all gravidities in Kisumu, Kenya. AIDS 17: pp. 595-603 lass="external" href="http://dx.doi.org/10.1097/00002030-200303070-00015" target="_blank" title="It opens in new window">CrossRef
43. Menendez, C, Ordi, J, Ismail, MR, Ventura, PJ, Aponte, JJ, Kahigwa, E, Font, F, Alonso, PL (2000) The impact of placental malaria on gestational age and birth weight. J Infect Dis 181: pp. 1740-1745 lass="external" href="http://dx.doi.org/10.1086/315449" target="_blank" title="It opens in new window">CrossRef
44. Guyatt, HL, Snow, RW (2004) Impact of malaria during pregnancy on low birth weight in sub-Saharan Africa. Clin Microbiol Rev 17: pp. 760-769 lass="external" href="http://dx.doi.org/10.1128/CMR.17.4.760-769.2004" target="_blank" title="It opens in new window">CrossRef
45. Steketee, RW (2002) Malaria prevention in pregnancy: when will the prevention programme respond to the science. J Health Popul Nutr 20: pp. 1-3
46. McDonald, CR, Elphinstone, RE, Kain, KC (2013) The impact of placental malaria on neurodevelopment of exposed infants: a role for the complement system?. Trends Parasitol 29: pp. 213-219 lass="external" href="http://dx.doi.org/10.1016/j.pt.2013.03.005" target="_blank" title="It opens in new window">CrossRef
47. Ismaili, J, van der Sande, M, Holland, MJ, Sambou, I, Keita, S, Allsopp, C, Ota, MO, Mcadam, KPWJ (2003) Plasmodium falciparum infection of the placenta affects newborn. Clin Exp Immunol 133: pp. 414-421 lass="external" href="http://dx.doi.org/10.1046/j.1365-2249.2003.02243.x" target="_blank" title="It opens in new window">CrossRef
48. Huynh, B-T, Fievet, N, Gbaguidi, G, Dechavanne, S, Borgella, S, Gu茅zo-M茅vo, B, Massougbodji, A, Ndam, NT, Deloron, P, Cot, M (2011) Influence of the timing of malaria infection during pregnancy on birth weight and on maternal anemia in Benin. Am J Trop Med Hyg 85: pp. 214-220 lass="external" href="http://dx.doi.org/10.4269/ajtmh.2011.11-0103" target="_blank" title="It opens in new window">CrossRef
49. Bardaj铆, A, Bassat, Q, Alonso, PL, Men茅ndez, C (2012) Intermittent preventive treatment of malaria in pregnant women and infants: making best use of the available evidence. Expert Opin Pharmacother 13: pp. 1719-1736 lass="external" href="http://dx.doi.org/10.1517/14656566.2012.703651" target="_blank" title="It opens in new window">CrossRef
50. Valea, I, Tinto, H, Drabo, MK, Huybregts, L, Sorgho, H, Ouedraogo, J, Guiguemde, RT, Van Geertruyden, JP, Kolsteren, P, Alessandro, UD, Misame, FSP (2012) An analysis of timing and frequency of malaria infection during pregnancy in relation to the risk of low birth weight, anaemia and perinatal mortality in Burkina Faso. Malar J 11: pp. 71 lass="external" href="http://dx.doi.org/10.1186/1475-2875-11-71" target="_blank" title="It opens in new window">CrossRef
51. Kalilani-Phiri, L, Thesing, PC, Nyirenda, OM, Mawindo, P, Madanitsa, M, Membe, G, Wylie, B, Masonbrink, A, Makwakwa, K, Kamiza, S, Muehlenbachs, A, Taylor, TE, Laufer, MK (2013) Timing of malaria infection during pregnancy has characteristic maternal, infant and placental outcomes. PLoS One 8: pp. e74643 lass="external" href="http://dx.doi.org/10.1371/journal.pone.0074643" target="_blank" title="It opens in new window">CrossRef
52. Kayentao, K, Garner, P, van Eijk, AM, Naidoo, I, Mulokozi, A, Macarthur, JR, Luntamo, M, Ashorn, P, Doumbo, OK, ter Kuile, FO (2013) Intermittent preventive therapy for malaria during pregnancy using 2 vs 3 or more doses of sulfadoxine-pyrimethamine and risk of low birth weight in Africa. JAMA 309: pp. 594-604 lass="external" href="http://dx.doi.org/10.1001/jama.2012.216231" target="_blank" title="It opens in new window">CrossRef
Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of September 2013 meeting. Malar J 12: pp. 456 lass="external" href="http://dx.doi.org/10.1186/1475-2875-12-456" target="_blank" title="It opens in new window">CrossRef
53. Ter Kuile, FO, van Eijk, AM, Filler, SJ (2007) Resistance on the efficacy of intermittent preventive therapy. J Am Med Assoc 297: pp. 2603-2616 lass="external" href="http://dx.doi.org/10.1001/jama.297.23.2603" target="_blank" title="It opens in new window">CrossRef
54. Men茅ndez, C, Bardaj铆, A, Sigauque, B, Romagosa, C, Sanz, S, Serra-Casas, E, Macete, E, Berenguera, A, David, C, Doba帽o, C, Naniche, D, Mayor, A, Ordi, J, Mandomando, I, Aponte, JJ, Mabunda, S, Alonso, PL (2008) A randomized placebo-controlled trial of intermittent preventive treatment in pregnant women in the context of insecticide treated nets delivered through the antenatal clinic. PLoS One 3: pp. e1934 lass="external" href="http://dx.doi.org/10.1371/journal.pone.0001934" target="_blank" title="It opens in new window">CrossRef
55. Kayentao, K, Kodio, M, Newman, RD, Maiga, H, Doumtabe, D, Ongoiba, A, Coulibaly, D, Keita, AS, Maiga, B, Mungai, M, Parise, ME, Doumbo, O (2005) Comparison of intermittent preventive treatment with chemoprophylaxis for the prevention of malaria during pregnancy in Mali. J Infect Dis 191: pp. 109-116 lass="external" href="http://dx.doi.org/10.1086/426400" target="_blank" title="It opens in new window">CrossRef
56. Schultz, LJ, Steketee, RW, Macheso, A, Kazembe, P, Chitsulo, L, Wirima, JJ (1994) The efficacy of antimalarial regimens containing sulfadoxine-pyrimethamine and/or chloroquine in preventing peripheral and placental Plasmodium falciparum infection among pregnant women in Malawi. Am J Trop Med Hyg 51: pp. 515-522
57. McClure, EM, Goldenberg, RL, Dent, AE, Meshnick, SR (2013) A systematic review of the impact of malaria prevention in pregnancy on low birth weight and maternal anemia. Int J Gynaecol Obstet 121: pp. 103-109 lass="external" href="http://dx.doi.org/10.1016/j.ijgo.2012.12.014" target="_blank" title="It opens in new window">CrossRef
58. Diakite, OSM, Maiga, OM, Kayentao, K, Traor茅, BT, Djimde, A, Traor茅, B, Diallo, M, Traor茅, M, Ongoiba, A, Doumtab茅, D, Doumbo, S, Traor茅, MS, Dara, A, Guindo, O, Karim, DM, Coulibaly, S, Bougoudogo, F, Ter Kuile, FO, Danis, M, Doumbo, OK (2011) Superiority of 3 over 2 doses of intermittent preventive treatment with sulfadoxine-pyrimethamine for the prevention of malaria during pregnancy in mali: a randomized controlled trial. Clin Infect Dis 53: pp. 215-223 lass="external" href="http://dx.doi.org/10.1093/cid/cir374" target="_blank" title="It opens in new window">CrossRef
59. Briand, V, Bottero, J, No毛l, H, Masse, V, Cordel, H, Guerra, J, Kossou, H, Fayomi, B, Ayemonna, P, Fievet, N, Massougbodji, A, Cot, M (2009) Intermittent treatment for the prevention of malaria during pregnancy in Benin: a randomized, open-label equivalence trial comparing sulfadoxine-pyrimethamine with mefloquine. J Infect Dis 200: pp. 991-1001 lass="external" href="http://dx.doi.org/10.1086/605474" target="_blank" title="It opens in new window">CrossRef
60. Gutman, J, Mwandama, D, Wiegand, RE, Ali, D, Mathanga, DP, Skarbinski, J (2013) Effectiveness of intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy on maternal and birth outcomes in Machinga district, Malawi. J Infect Dis 208: pp. 907-916 lass="external" href="http://dx.doi.org/10.1093/infdis/jit276" target="_blank" title="It opens in new window">CrossRef
61. Harrington, WE, Mutabingwa, TK, Kabyemela, E, Fried, M, Duffy, PE (2011) Intermittent treatment to prevent pregnancy malaria does not confer benefit in an area of widespread drug resistance. Clin Infect Dis 53: pp. 224-230 lass="external" href="http://dx.doi.org/10.1093/cid/cir376" target="_blank" title="It opens in new window">CrossRef
62. Harrington, WE, Morrison, R, Fried, M, Duffy, PE (2013) Intermittent preventive treatment in pregnant women is associated with increased risk of severe malaria in their offspring. PLoS One 8: pp. e56183 lass="external" href="http://dx.doi.org/10.1371/journal.pone.0056183" target="_blank" title="It opens in new window">CrossRef
63. Taylor, SM, Antonia, AL, Chaluluka, E, Mwapasa, V, Feng, G, Molyneux, ME, ter Kuile, FO, Meshnick, SR, Rogerson, SJ (2012) Antenatal receipt of sulfadoxine-pyrimethamine does not exacerbate pregnancy-associated malaria despite the expansion of drug-resistant Plasmodium falciparum: clinical outcomes from the QuEERPAM study. Clin Infect Dis 55: pp. 42-50 lass="external" href="http://dx.doi.org/10.1093/cid/cis301" target="_blank" title="It opens in new window">CrossRef
64. Tagbor, H, Bruce, J, Agbo, M, Greenwood, B, Chandramohan, D (2010) Intermittent screening and treatment versus intermittent preventive treatment of malaria in pregnancy: a randomised controlled non-inferiority trial. PLoS One 5: pp. e14425 lass="external" href="http://dx.doi.org/10.1371/journal.pone.0014425" target="_blank" title="It opens in new window">CrossRef
65. Taylor, SM, Antonia, AL, Mwapasa, V, Feng, G, Molyneux, ME, ter Kuile, FO, Meshnick, SR, Rogerson, SJ (2012) Reply to Harrington et al. Clin Infect Dis 55: pp. 1026-1027 lass="external" href="http://dx.doi.org/10.1093/cid/cis570" target="_blank" title="It opens in new window">CrossRef - 刊物主题：Parasitology; Infectious Diseases; Tropical Medicine;
- 出版者：BioMed Central
- ISSN：1475-2875
文摘
Albeit pregnancy-associated malaria (PAM) poses a potential risk for over 125 million women each year, an accurate review assessing the impact on malaria in infants has yet to be conducted. In addition to an effect on low birth weight (LBW) and prematurity, PAM determines foetal exposure to Plasmodium falciparum in utero and is correlated to congenital malaria and early development of clinical episodes during infancy. This interaction plausibly results from an ongoing immune tolerance process to antigens in utero, however, a complete explanation of this immune process remains a question for further research, as does the precise role of protective maternal antibodies. Preventive interventions against PAM modify foetal exposure to P. falciparum in utero, and have thus an effect on perinatal malaria outcomes. Effective intermittent preventive treatment in pregnancy (IPTp) diminishes placental malaria (PM) and its subsequent malaria-associated morbidity. However, emerging resistance to sulphadoxine-pyrimethamine (SP) is currently hindering the efficacy of IPTp regimes and the efficacy of alternative strategies, such as intermittent screening and treatment (IST), has not been accurately evaluated in different transmission settings. Due to the increased risk of clinical malaria for offspring of malaria infected mothers, PAM preventive interventions should ideally start during the preconceptual period. Innovative research examining the effect of PAM on the neurocognitive development of the infant, as well as examining the potential influence of HLA-G polymorphisms on malaria symptoms, is urged to contribute to a better understanding of PAM and infant health.