Global burden, distribution, and interventions for infectious diseases of poverty
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  • 作者:Zulfiqar A Bhutta (1) (2)
    Johannes Sommerfeld (3)
    Zohra S Lassi (4)
    Rehana A Salam (4)
    Jai K Das (4)

    1. Center of Excellence in Women & Child Health
    ; The Aga Khan University ; Karachi ; Pakistan
    2. Center for Global Child Health Hospital for Sick Children
    ; Toronto ; Canada
    3. UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR)
    ; Geneva ; Switzerland
    4. Division of Women and Child Health
    ; The Aga Khan University ; Karachi ; Pakistan
  • 关键词:Infectious diseases of poverty ; Neglected tropical diseases malaria ; HIV/AIDS ; Tuberculosis ; Community ; based interventions ; Community platforms ; Community ; health workers
  • 刊名:Infectious Diseases of Poverty
  • 出版年:2014
  • 出版时间:December 2014
  • 年:2014
  • 卷:3
  • 期:1
  • 全文大小:507 KB
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  • 刊物主题:Infectious Diseases; Tropical Medicine;
  • 出版者:BioMed Central
  • ISSN:2049-9957
文摘
Infectious diseases of poverty (IDoP) disproportionately affect the poorest population in the world and contribute to a cycle of poverty as a result of decreased productivity ensuing from long-term illness, disability, and social stigma. In 2010, the global deaths from HIV/AIDS have increased to 1.5 million and malaria mortality rose to 1.17 million. Mortality from neglected tropical diseases rose to 152,000, while tuberculosis killed 1.2 million people that same year. Substantial regional variations exist in the distribution of these diseases as they are primarily concentrated in rural areas of Sub-Saharan Africa, Asia, and Latin America, with geographic overlap and high levels of co-infection. Evidence-based interventions exist to prevent and control these diseases, however, the coverage still remains low with an emerging challenge of antimicrobial resistance. Therefore, community-based delivery platforms are increasingly being advocated to ensure sustainability and combat co-infections. Because of the high morbidity and mortality burden of these diseases, especially in resource-poor settings, it is imperative to conduct a systematic review to identify strategies to prevent and control these diseases. Therefore, we attempted to evaluate the effectiveness of one of these strategies, that is community-based delivery for the prevention and treatment of IDoP. In this paper, we describe the burden, epidemiology, and potential interventions for IDoP. In subsequent papers of this series, we describe the analytical framework and the methodology used to guide the systematic reviews, and report the findings and interpretations of our analyses of the impact of community-based strategies on individual IDoPs.

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