Depth-dependent changes of obstruction patterns under increasing sedation during drug-induced sedation endoscopy: results of a German monocentric clinical trial
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- 作者：Patrick Kellner ; Beatrice Herzog ; Sebastian Plößl…
- 关键词：Drug ; induced sedation endoscopy ; DISE ; Simulated snoring ; BIS ; Sedation depth ; Propofol
- 刊名：Sleep and Breathing
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：20
- 期：3
- 页码：1035-1043
- 全文大小：781 KB
- 刊物主题：Pneumology/Respiratory System; Otorhinolaryngology; Dentistry; Neurology; Internal Medicine; Pediatrics;
- 出版者：Springer Berlin Heidelberg
- ISSN：1522-1709
- 卷排序：20
文摘
PurposeDrug-induced sedation endoscopy (DISE) and simulated snoring (SimS) can locate the site of obstruction in patients with sleep-disordered breathing (SDB). There is clinical evidence for a change in collapsibility of the upper airway depending on the depth of sedation. So far, a dose-response relationship between sedation and collapsibility has not been demonstrated.