Moderate-to-deep sedation technique, using propofol and ketamine, allowing synchronised breathing for magnetic resonance high-intensity focused ultrasound (MR-HIFU) treatment for uterine fibroids: a pilot study

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• 作者：Hermanus H. B. Vaessen ; F. M. Knuttel…
• 关键词：Deep propofol and esketamine sedation ; Safety ; MR ; HIFU uterine fibroids treatment ; Hallucinations and sedation ; related complications
• 刊名：Journal of Therapeutic Ultrasound
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：5
• 期：1
• 全文大小：385KB
• 刊物主题：Ultrasound; Imaging / Radiology;
• 出版者：BioMed Central
• ISSN：2050-5736
• 卷排序：5

文摘

BackgroundMagnetic resonance high-intensity focused ultrasound (MR-HIFU) treatment for uterine fibroids is rapidly gaining popularity as a treatment modality. This procedure is generally uncomfortable, painful, and requires minimal or absence of movement and an MR-HIFU synchronised breathing pattern of the patient. Procedural sedation and analgesia protocols have become the standard practice in interventional radiology departments worldwide. The aim of this study was to explore if a sedation regimen with low-dose propofol and ketamine performed by trained non-medical sedation practitioners could result in relief of discomfort for the patient and in adequate working conditions for MR-HIFU treatment for uterine fibroids.