Inhibitory effect of flavonoids against NS2B-NS3 protease of ZIKA virus and their structure activity relationship

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• 作者：Hee-jung Lim ; Thi Thanh Hanh Nguyen ; Nahyun M. Kim ; Jun-Seong Park…
• 关键词：Flavanoids ; Myricetin ; Polyphenols ; Protease ; Zika virus
• 刊名：Biotechnology Letters
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：39
• 期：3
• 页码：415-421
• 全文大小：
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Microbiology; Biotechnology; Applied Microbiology; Biochemistry, general;
• 出版者：Springer Netherlands
• ISSN：1573-6776
• 卷排序：39

文摘

ObjectivesTo determine the inhibitory activities of flavonoids against NS2B-NS3 protease of ZIKA virus (ZIKV NS2B-NS3pro) expressed in Escherichia coli BL21 (DE3) and their structure activity relationship.