Fertility as a priority among at-risk adolescent males newly diagnosed with cancer and their parents
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- 作者：James L. Klosky ; Jessica L. Simmons ; Kathryn M. Russell…
- 关键词：Fertility ; Sperm banking ; Cancer ; Oncology ; Adolescents ; Parents
- 刊名：Supportive Care in Cancer
- 出版年：2015
- 出版时间：February 2015
- 年：2015
- 卷：23
- 期：2
- 页码：333-341
- 全文大小：404 KB
- 参考文献：1. Schrader M, Müller M, Straub B et al (2001) The impact of chemotherapy on male fertility: a survey of the biologic basis and clinical aspects. Reprod Toxicol 15:611-17. doi:10.1016/S0890-6238(01)00182-4 CrossRef
2. Thomson AB, Campbell AJ, Irvin DS et al (2002) Semen quality and spermatozoal DNA integrity in survivors of childhood cancer: a case–control study. Lancet 360:361-67. doi:10.1016/S0140-6736(02)09606-X CrossRef
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11. Quinn GP, Knapp C, Murphy D, Sawczyn K, Sender L (2012) Congruence of reproductive concerns among adolescents with cancer and parents: pilot testing an adapted instrument. Pediatrics 129(4):e930–e936. doi:10.1542/peds.2011-2568 CrossRef
12. Burns KC, Boudreau C, Panepinto JA (2006) Attitudes regarding fertility preservation in female adolescent cancer patients. J Pediatr Hematol Oncol 28:350-54 CrossRef
13. Oosterhuis EB, Goodwin T, Kiernan M et al (2008) Concerns about infertility risks among pediatric oncology patients and their parents. Pediatr Blood Cancer 50:85-9. doi:10.1002/pbc.21261 CrossRef
14. Achille MA, Rosberger Z, Robitaille R et al (2006) Facilitators and obstacles to sperm banking in young men receiving gonadotoxic chemotherapy for cancer: the perspective of survivors and health care professionals. Hum Reprod 21:3206-216. doi:10.1093/humrep/del307- 刊物类别：Medicine
- 刊物主题：Medicine & Public Health
Oncology
Nursing
Nursing Management and Research
Pain Medicine
Rehabilitation Medicine- 出版者：Springer Berlin / Heidelberg
- ISSN：1433-7339
文摘
Purpose Infertility is a frequent consequence of cancer therapy and is often associated with psychological distress. Although adult survivors prioritize fertility and parenthood, this issue remains unexplored among adolescent males. This study examined future fertility as a priority (relative to other life goals) at time of diagnosis for at-risk adolescents and their parents. Methods Newly diagnosed adolescent males (n--6; age--3.0-1.9?years) at increased risk for infertility secondary to cancer treatment prioritized eight life goals: to have school/work success, children, friends, wealth, health, a nice home, faith, and a romantic relationship. Patients-parents (fathers, n--0; mothers, n--1) rank-ordered the same priorities for their children. Results “Having children-was ranked as a “top 3-life goal among 43.8?% of adolescents, 36.7?% of fathers, and 21.3?% of mothers. Fertility ranked third among adolescents, fourth among fathers, and fifth among mothers. Future health was ranked the top priority across groups, distinct from all other goals (ps--.001), and fertility ranked higher than home ownership and wealth for all groups (ps--.001). For adolescents, low/moderate fertility risk perception was associated with higher fertility rankings than no/high risk perceptions (p--.01). Conclusions Good health is the most important life goal among adolescents newly diagnosed with cancer and their parents. In this relatively small sample, adolescents prioritized fertility as a top goal, parents also rated fertility as being more important than home ownership and financial wealth. Health care providers should communicate fertility risk and preservation options at diagnosis and facilitate timely discussion among families, who may differ in prioritization of future fertility.