Sleep and Cognitive Abnormalities in Acute Minor Thalamic Infarction

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• 作者：Wei Wu ; Linyang Cui ; Ying Fu ; Qianqian Tian ; Lei Liu ; Xuan Zhang…
• 刊名：Neuroscience Bulletin
• 出版年：2016
• 出版时间：August 2016
• 年：2016
• 卷：32
• 期：4
• 页码：341-348
• 全文大小：828 KB
• 刊物主题：Neurosciences; Human Physiology; Anesthesiology; Anatomy; Neurology; Pain Medicine;
• 出版者：Springer Berlin Heidelberg
• ISSN：1995-8218
• 卷排序：32

文摘

In order to characterize sleep and the cognitive patterns in patients with acute minor thalamic infarction (AMTI), we enrolled 27 patients with AMTI and 12 matched healthy individuals. Questionnaires about sleep and cognition as well as polysomnography (PSG) were performed on days 14 and 90 post-stroke. Compared to healthy controls, in patients with AMTI, hyposomnia was more prevalent; sleep architecture was disrupted as indicated by decreased sleep efficiency, increased sleep latency, and decreased non-rapid eye movement sleep stages 2 and 3; more sleep-related breathing disorders occurred; and cognitive functions were worse, especially memory. While sleep apnea and long-delay memory recovered to a large extent in the patients, other sleep and cognitive function deficit often persisted. Patients with AMTI are at an increased risk for hyposomnia, sleep structure disturbance, sleep apnea, and memory deficits. Although these abnormalities improved over time, the slow and incomplete improvement suggest that early management should be considered in these patients.KeywordsAcute minor thalamic infarctionPolysomnographyCognition