Long noncoding RNA NEAT1 promotes laryngeal squamous cell cancer through regulating miR-107/CDK6 pathway

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• 作者：Peng Wang ; Tianyi Wu ; Han Zhou ; Qianqian Jin…
• 关键词：Laryngeal squamous cell cancer ; Long noncoding RNA ; microRNA ; NEAT1 ; CDK6 ; miR ; 107
• 刊名：Journal of Experimental & Clinical Cancer Research
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：35
• 期：1
• 全文大小：1,091 KB
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• 作者单位：Peng Wang (1)
  Tianyi Wu (1)
  Han Zhou (1)
  Qianqian Jin (1)
  Guoqing He (1)
  Haoyang Yu (1)
  Lijia Xuan (1)
  Xin Wang (1)
  Linli Tian (1)
  Yanan Sun (1)
  Ming Liu (1)
  Lingmei Qu (2)
  
  1. Department of Otorhinolaryngology, Head and Neck Surgery, The Second Affiliated Hospital, Harbin Medical University, No. 246, Baojian Road, Harbin, 150086, China
  2. Department of Otorhinolaryngology, Head and Neck Surgery, The Fifth Affiliated Hospital, Harbin Medical University, No. 213, Jianshe Road, Daqing, China
  
• 刊物主题：Oncology; Cancer Research;
• 出版者：BioMed Central
• ISSN：1756-9966

文摘

Background Long noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1) plays key role in the progression of some human cancers. However, the role of NEAT1 in human laryngeal squamous cell cancer (LSCC) is still unknown. We therefore investigated the expression and function of NEAT1 in LSCC.