Cognitive deficits in adults with obstructive sleep apnea compared to children and adolescents

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• 作者：Krzysztof Krysta ; Agnieszka Bratek ; Karolina Zawada…
• 关键词：Sleep apnea syndromes ; Cognitive science ; Obstructive sleep apnea ; Neuroimaging ; Neuropsychological tests
• 刊名：Journal of Neural Transmission
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：124
• 期：1-supp
• 页码：187-201
• 全文大小：506KB
• 刊物类别：Medicine
• 刊物主题：Neurology; Psychiatry; Pharmacology/Toxicology; Neurosciences;
• 出版者：Springer Vienna
• ISSN：1435-1463
• 卷排序：124

文摘

Obstructive sleep apnea (OSA) can negatively affect the patient’s physical and psychological functioning, as well as their quality of life. A major consequence of OSA is impaired cognitive functioning. Indeed, several studies have shown that OSA mainly leads to deficits in executive functions, attention, and memory. As OSA can present in all age groups, these associated cognitive deficits have been observed in adults, as well as in children and adolescents. However, these cognitive deficits may have a different clinical picture in young patients compared to adults. In this review, we analyze the most affected cognitive domains in adults and children/adolescents with OSA, as evaluated by neuropsychological and neuroimaging studies. We found that deficits in working memory, attention, or executive functions cognitive domains are found in both adults and children with OSA. However, children with OSA also show changes in behavior and phonological processing necessary for proper development. Moreover, we examine the possible OSA treatments in children and adults that can have a positive influence on cognition, and therefore, improve patients’ general functioning and quality of life.