Multilevel pharmacokinetics-driven modeling of metabolomics data
详细信息 查看全文
- 作者：Emilia Daghir-Wojtkowiak ; Paweł Wiczling ; Małgorzata Waszczuk-Jankowska…
- 关键词：Multi ; level modeling ; Bayesian analysis ; Pharmacokinetics ; Metabolomics ; Nucleosides ; Methylthioadenosine ; Cancer
- 刊名：Metabolomics
- 出版年：2017
- 出版时间：March 2017
- 年：2017
- 卷：13
- 期：3
- 全文大小：3582KB
- 刊物主题：Biochemistry, general; Molecular Medicine; Cell Biology; Developmental Biology; Biomedicine, general;
- 出版者：Springer US
- ISSN：1573-3890
- 卷排序：13
文摘
IntroductionMultilevel modeling is a quantitative statistical method to investigate variability and relationships between variables of interest, taking into account population structure and dependencies. It can be used for prediction, data reduction and causal inference from experiments and observational studies allowing for more efficient elucidation of knowledge.