New Insights into Ragweed Pollen Allergens

详细信息    查看全文

• 作者：Véronique Bordas-Le Floch ; Rachel Groeme…
• 关键词：Allergens ; Ambrosia artemisiifolia ; Mass spectrometry ; RNA sequencing ; Short ragweed
• 刊名：Current Allergy and Asthma Reports
• 出版年：2015
• 出版时间：November 2015
• 年：2015
• 卷：15
• 期：11
• 全文大小：457 KB
• 参考文献：Papers of particular interest, published recently, have been highlighted as: -Of importance ?-Of major importance1.Rybncek O, J?ger S. Ambrosia (ragweed) in Europe. Allergy Clin Immunol Int. 2001;13(2):60-.CrossRef
  2.Arbes Jr SJ, Gergen PJ, Elliott L, Zeldin DC. Prevalences of positive skin test responses to 10 common allergens in the US population: results from the third National Health and Nutrition Examination Survey. J Allergy Clin Immunol. 2005;116(2):377-3.CrossRef PubMed
  3.Taramarcaz P, Lambelet B, Clot B, Keimer C, Hauser C. Ragweed (Ambrosia) progression and its health risks: will Switzerland resist this invasion? Swiss Med Wkly. 2005;135(37-8):538-8.PubMed
  4.D’Amato G, Cecchi L, Bonini S, Nunes C, Annesi-Maesano I, Behrendt H, et al. Allergenic pollen and pollen allergy in Europe. Allergy. 2007;62(9):976-0.CrossRef PubMed
  5.Burbach GJ, Heinzerling LM, Rohnelt C, Bergmann KC, Behrendt H, Zuberbier T. Ragweed sensitization in Europe—GA(2)LEN study suggests increasing prevalence. Allergy. 2009;64(4):664-.CrossRef PubMed
  6.Ru?ff F, Przybilla B, Walker A, Gmeiner J, Kramer M, Sabanés-Bové D, et al. Sensitization to common ragweed in Southern Bavaria: clinical and geographical risk factors in atopic patients. Int Arch Allergy Immunol. 2012;159(1):65-4.CrossRef PubMed
  7.Fumanal B, Chauvel B, Bretagnolle F. Estimation of pollen and seed production of common ragweed in France. Ann Agric Environ Med. 2007;14(2):233-.PubMed
  8.Smith M, Cecchi L, Skj?th CA, Karrer G, ?ikoparija B. Common ragweed: a threat to environmental health in Europe. Environ Int. 2013;61:115-6.CrossRef PubMed
  9.Oswalt ML, Marshall GD. Ragweed as an example of worldwide allergen expansion. Allergy Asthma Clin Immunol. 2008;4(3):130-.PubMed Central CrossRef PubMed
  10.Hamaoui-Laguel L, Vautard R, Liu L, Solmon F, Viovy N, Khvorosthyanov D, et al. Effects of climate change and seed dispersal on airborne ragweed pollen loads in Europe. Nat Clim Chang. 2015. doi:10.-038/?nclimate2652 .
  11.Pashley CH, Satchwell J, Edwards RE. Ragweed pollen: is climate change creating a new aeroallergen problem in the UK? Clin Exp Allergy. 2015. doi:10.-111/?cea.-2572 .PubMed
  12.D’Amato G, Cecchi L. Effects of climate change on environmental factors in respiratory allergic diseases. Clin Exp Allergy. 2008;38(8):1264-4.CrossRef PubMed
  13.Ziska L, Knowlton K, Rogers C, Dalan D, Tierney N, Elder MA, et al. Recent warming by latitude associated with increased length of ragweed pollen season in central North America. Proc Natl Acad Sci U S A. 2011;108(10):4248-1.PubMed Central CrossRef PubMed
  14.Ghiani A, Aina R, Asero R, Bellotto E, Citterio S. Ragweed pollen collected along high-traffic roads shows a higher allergenicity than pollen sampled in vegetated areas. Allergy. 2012;67(7):887-4.CrossRef PubMed
  15.?-/div>Kanter U, Heller W, Durner J, Winkler JB, Engel M, Behrendt H, et al. Molecular and immunological characterization of ragweed (Ambrosia artemisiifolia L.) pollen after exposure of the plants to elevated ozone over a whole growing season. PLoS One. 2013;8(4):e61518. In depth analysis of the impact of ozone exposure on A. artemisiifolia pollen. This paper reports the first transcriptome analysis of ragweed pollen performed using deep sequencing technologies.PubMed Central CrossRef PubMed
  16.-/div>El Kelish A, Zhao F, Heller W, Durner J, Winkler JB, Behrendt H, et al. Ragweed (Ambrosia artemisiifolia) pollen allergenicity: SuperSAGE transcriptomic analysis upon elevated CO2 and drought stress. BMC Plant Biol. 2014;14:176. Analysis of changes in transcriptome of ragweed pollen upon drought conditions or following exposure to CO2.PubMed Central CrossRef PubMed
  17.-/div>Zhao F, Elkelish A, Durner J, Lindermayr C, Winkler JB, Ru?ff F, et al. Common ragweed (Ambrosia artemisiifolia L.): allergenicity and molecular characterisation of pollen after plant exposure to elevated NO2. Plant Cell Environ. 2015. doi:10.-111/?pce.-2601 . Analysis of molecular changes induced in ragweed pollen following exposure to NO2.
  18.Wopfner N, Gadermaier G, Egger M, Asero R, Ebner C, Jahn-Schmid B, et al. The spectrum of allergens in ragweed and mugwort pollen. Int Arch Allergy Immunol. 2005;138(4):337-6.CrossRef PubMed
  19.?-/div>Gadermaier G, Hauser M, Ferreira F. Allergens of weed pollen: an overview on recombinant and natural molecules. Methods. 2014;66(1):55-6. Recent and comprehensive review of known ragweed allergens and their recombinant counterparts.CrossRef PubMed
  20.?-/div>Bouley J, Groeme R, Le Mignon M, Jain K, Chabre H, Bordas-Le Floch V, et al. Identification of the cysteine protease Amb a 11 as a novel major allergen from short ragweed. J Allergy Clin Immunol. 2015. doi:10.-016/?j.?jaci.-015.-3.-01 . First report on the identification and characterization of Amb a 11 as a novel major allergen from ragweed pollen.PubMed
  21.Nandy A, Augustin S, Mitulski L, Cromw
• 作者单位：Véronique Bordas-Le Floch (1)
  Rachel Groeme (1)
  Henri Chabre (1)
  Véronique Baron-Bodo (1)
  Emmanuel Nony (1)
  Laurent Mascarell (1)
  Philippe Moingeon (1)
  
  1. Stallergenes, 6 rue Alexis de Tocqueville, 92183, Antony cedex, France
  
• 刊物主题：Allergology;
• 出版者：Springer US
• ISSN：1534-6315

文摘

Pollen allergens from short ragweed (Ambrosia artemisiifolia) cause severe respiratory allergies in North America and Europe. To date, ten short ragweed pollen allergens belonging to eight protein families, including the recently discovered novel major allergen Amb a 11, have been recorded in the International Union of Immunological Societies (IUIS) allergen database. With evidence that other components may further contribute to short ragweed pollen allergenicity, a better understanding of the allergen repertoire is a requisite for the design of proper diagnostic tools and efficient immunotherapies. This review provides an update on both known as well as novel candidate allergens from short ragweed pollen, identified through a comprehensive characterization of the ragweed pollen transcriptome and proteome. Keywords Allergens Ambrosia artemisiifolia Mass spectrometry RNA sequencing Short ragweed