Is allergic sensitization relevant in severe asthma? Which allergens may be culprits?
详细信息 查看全文
- 作者：Carlo Lombardi ; Eleonora Savi ; Erminia Ridolo…
- 关键词：Severe asthma ; Atopy ; Allergic sensitization ; Allergens
- 刊名：World Allergy Organization Journal
- 出版年：2017
- 出版时间：December 2017
- 年：2017
- 卷：10
- 期：1
- 全文大小：411KB
- 刊物主题：Allergology; Immunology;
- 出版者：BioMed Central
- ISSN：1939-4551
- 卷排序：10
文摘
Severe asthma is a major health concern. The allergic (IgE-mediated) form of asthma is well known from a pathogenic viewpoint. We searched the available literature to identify which allergens are most frequently associated with severe, refractory or life threatening asthma. According to the results, molds, pet dander, cockroach and ragweed were more frequently responsible for severe asthma. Thunderstorm asthma, in addition, represents a special association between allergic sensitization and an external climatic factor. A detailed knowledge of the most harmful allergens is mandatory for an appropriate diagnostic and preventive approach.