Selective retina therapy (SRT) in patients with geographic atrophy due to age-related macular degeneration
详细信息 查看全文
- 作者：Philipp Prahs ; Andreas Walter ; Roman Regler ; Dirk Theisen-Kunde ; Reginald Birngruber ; Ralf Brinkmann and Carsten Framme
- 关键词：Geographic atrophy ; AMD ; RPE ; Laser photocoagulation ; SRT ; Selective retina treatment
- 刊名：Graefe's Archive for Clinical and Experimental Ophthalmology
- 出版年：2010
- 出版时间：May, 2010
- 年：2010
- 卷：248
- 期：5
- 页码：651-658
- 全文大小：391.7 KB
文摘
Background For geographic atrophy (GA) due to age-related macular degeneration (AMD) there is so far no approved treatment option. Usually, increased autofluorescence (AF) levels of different patterns adjacent to the atrophic area indicate lipofuscin-laden retinal pigment epithelium (RPE) cells at a high risk for apoptosis. Herein, SRT was used to selectively treat these cells to stimulate RPE proliferation, in order to reduce or ideally stop further growth of the atrophic area.