Genome-wide association study in Chinese Holstein cows reveal two candidate genes for somatic cell score as an indicator for mastitis susceptibility
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- 作者：Xiao Wang ; Peipei Ma ; Jianfeng Liu ; Qin Zhang ; Yuan Zhang ; Xiangdong Ding…
- 关键词：Genome ; wide association study ; EBVs of somatic cell scores ; Chinese Holstein cows ; Mixed model based single locus regression analysis ; Mastitis susceptibility
- 刊名：BMC Genetics
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：16
- 期：1
- 全文大小：1,305 KB
- 刊物主题：Life Sciences, general; Animal Genetics and Genomics; Microbial Genetics and Genomics; Plant Genetics & Genomics; Genetics and Population Dynamics;
- 出版者：BioMed Central
- ISSN：1471-2156
文摘
Backgrounds Bovine mastitis is a typical inflammatory disease causing seriously economic loss. Genome-wide association study (GWAS) can be a powerful method to promote marker assistant selection of this kind of complex disease. The present study aimed to analyze and identify single nucleotide polymorphisms (SNPs) and candidate genes that associated with mastitis susceptibility traits in Chinese Holstein.