Manually defining regions of interest when quantifying paravertebral muscles fatty infiltration from axial magnetic resonance imaging: a proposed method for the lumbar spine with anatomical cross-reference

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• 作者：Rebecca J. Crawford ; Jon Cornwall ; Rebecca Abbott…
• 关键词：Lumbar spine ; Paravertebral muscles ; Fat infiltration ; Magnetic resonance imaging ; Region of interest ; Manual segmentation ; Multifidus ; Erector spinae
• 刊名：BMC Musculoskeletal Disorders
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：18
• 期：1
• 全文大小：1277KB
• 刊物主题：Orthopedics; Rehabilitation; Rheumatology; Sports Medicine; Internal Medicine; Epidemiology;
• 出版者：BioMed Central
• ISSN：1471-2474
• 卷排序：18

文摘

BackgroundThere is increasing interest in paravertebral muscle composition as a potential prognostic and diagnostic element in lumbar spine health. As a consequence, it is becoming popular to use magnetic resonance imaging (MRI) to examine muscle volume and fatty infiltration in lumbar paravertebral muscles to assess both age-related change and their clinical relevance in low back pain (LBP). A variety of imaging methods exist for both measuring key variables (fat, muscle) and for defining regions of interest, making pooled comparisons between studies difficult and rendering post-production analysis of MRIs confusing. We therefore propose and define a method as an option for use as a standardized MRI procedure for measuring lumbar paravertebral muscle composition, and to stimulate discussion towards establishing consensus for the analysis of skeletal muscle composition amongst clinician researchers.