Intrathecal Th17- and B cell-associated cytokine and chemokine responses in relation to clinical outcome in Lyme neuroborreliosis: a large retrospective study

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• 作者：Paula Gyllemark ; Pia Forsberg ; Jan Ernerudh…
• 关键词：Lyme neuroborreliosis ; Cerebrospinal fluid ; Cytokines ; Chemokines ; APRIL ; BAFF ; CCL20 ; CXCL 1 ; CXCL13 ; IL ; 17A
• 刊名：Journal of Neuroinflammation
• 出版年：2017
• 出版时间：December 2017
• 年：2017
• 卷：14
• 期：1
• 全文大小：669KB
• 刊物主题：Neurosciences; Neurology; Neurobiology; Immunology;
• 出版者：BioMed Central
• ISSN：1742-2094
• 卷排序：14

文摘

BackgroundB cell immunity, including the chemokine CXCL13, has an established role in Lyme neuroborreliosis, and also, T helper (Th) 17 immunity, including IL-17A, has recently been implicated.