The Preventive Effect of Calcium Supplementation on Weak Bones Caused by the Interaction of Exercise and Food Restriction in Young Female Rats During the Period from Acquiring Bone Mass to Maintaining Bone Mass

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• 作者：Yuki Aikawa ; Umon Agata ; Yuya Kakutani ; Shoyo Kato…
• 关键词：Young female athlete ; Inadequate food intake ; High ; Ca diet ; Bone strength ; Growing rat
• 刊名：Calcified Tissue International
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：98
• 期：1
• 页码：94-103
• 全文大小：445 KB
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• 作者单位：Yuki Aikawa (1)
  Umon Agata (1)
  Yuya Kakutani (1)
  Shoyo Kato (1)
  Yuichi Noma (1)
  Satoshi Hattori (1)
  Hitomi Ogata (2)
  Ikuko Ezawa (3)
  Naomi Omi (2) (4)
  
  1. Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8572, Japan
  2. Faculty of Health and Sport Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki, 305-8572, Japan
  3. Department of food and nutrition, Japan Women’s University, 2-8-1 Mejirodai, Bunkyo-Ku, Tokyo, 112-8681, Japan
  4. Institute of Health and Sports Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, 305-8574, Japan
  
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Life Sciences
  Biochemistry
  Endocrinology
  Orthopedics
  Cell Biology
  
• 出版者：Springer New York
• ISSN：1432-0827

文摘

Increasing calcium (Ca) intake is important for female athletes with a risk of weak bone caused by inadequate food intake. The aim of the present study was to examine the preventive effect of Ca supplementation on low bone strength in young female athletes with inadequate food intake, using the rats as an experimental model. Seven-week-old female Sprague-Dawley rats were divided into four groups: the sedentary and ad libitum feeding group (SED), voluntary running exercise and ad libitum feeding group (EX), voluntary running exercise and 30 % food restriction group (EX-FR), and a voluntary running exercise, 30 % food-restricted and high-Ca diet group (EX-FR+Ca). To Ca supplementation, we used 1.2 % Ca diet as “high-Ca diet” that contains two-fold Ca of normal Ca diet. The experiment lasted for 12 weeks. As a result, the energy availability, internal organ weight, bone strength, bone mineral density, and Ca absorption in the EX-FR group were significantly lower than those in the EX group. The bone strength and Ca absorption in the EX-FR+Ca group were significantly higher than those in the EX-FR group. However, the bone strength in the EX-FR+Ca group did not reach that in the EX group. These results suggested that Ca supplementation had a positive effect on bone strength, but the effect was not sufficient to prevent lower bone strength caused by food restriction in young female athletes. Keywords Young female athlete Inadequate food intake High-Ca diet Bone strength Growing rat