Acute low-intensity cycling with blood-flow restriction has no effect on metabolic signaling in human skeletal muscle compared to traditional exercise

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• 作者：William J. Smiles ; Miguel S. Conceição…
• 关键词：Blood ; flow restriction ; Exercise ; Autophagy ; Mitophagy
• 刊名：European Journal of Applied Physiology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：117
• 期：2
• 页码：345-358
• 全文大小：
• 刊物类别：Biomedical and Life Sciences
• 刊物主题：Human Physiology; Occupational Medicine/Industrial Medicine; Sports Medicine;
• 出版者：Springer Berlin Heidelberg
• ISSN：1439-6327
• 卷排序：117

文摘

PurposeAutophagy is an intracellular degradative system sensitive to hypoxia and exercise-induced perturbations to cellular bioenergetics. We determined the effects of low-intensity endurance-based exercise performed with blood-flow restriction (BFR) on cell signaling adaptive responses regulating autophagy and substrate metabolism in human skeletal muscle.