Erkrankungen des Bindegewebes bei IgG4-assoziierten Autoimmunerkrankungen

详细信息    查看全文

• 作者：Univ.-Prof. Dr. G. A. Krombach
• 关键词：SchlüsselwörterBindegewebeerkrankungen ; Fibrose ; Retroperitonealfibrose ; Sklerosierende Mesenteritis ; Sklerosierende Mediastinitis
• 刊名：Der Radiologe
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：56
• 期：12
• 页码：1061-1068
• 全文大小：
• 刊物类别：Medicine
• 刊物主题：Imaging / Radiology; General Practice / Family Medicine;
• 出版者：Springer Medizin
• ISSN：1432-2102
• 卷排序：56

文摘

The IgG4-associated diseases of connective tissue are caused by allergen-mediated autoimmune processes. The retroperitoneum, mesentery and mediastinum as well as other less common localizations, such as the neck, orbit and periarticular connective tissue can be affected. Inflammatory fibrosis is initially dominated by a lymphocytic and plasma cell-rich infiltrate and later by cell-poor storiform fibrosis. Stenosis and occlusion of vessels, ureters and intestines can cause severe complications. Computed tomography (CT) and magnetic resonance imaging (MRI) can be implemented in the diagnostic algorithm to narrow the differential diagnosis, delineate the distribution of fibrosis and reveal complications.